Anti-Influenza A antibody is a Mouse antibody of IgG class that binds to an Influenza A. This antibody was the first antibody to be described with heterosubtypic reactivity, neutralizing strains from multiple subtypes, such as H1, H2, H3, and H13, that cross the HA group barrier.
Figure 1 SDS-PAGE analysis of purified S139/1 IgA and IgG antibodies.
Equal amounts (2.5 mg) of purified S139/1 IgA and IgG antibodies were analyzed by SDS-PAGE under reducing conditions (5%–20% gradient gel) (A). Polymeric forms of purified S139/1 IgA and IgG antibodies (5 mg) were analyzed under nonreducing conditions (3%–10% gradient gel) (B).
Muramatsu, M., Yoshida, R., Yokoyama, A., Miyamoto, H., Kajihara, M., Maruyama, J., ... & Takada, A. (2014). Comparison of antiviral activity between IgA and IgG specific to influenza virus hemagglutinin: increased potential of IgA for heterosubtypic immunity. PLoS One, 9(1), e85582.
Figure 2 Comparison of binding activities of S139/1 IgA and IgG antibodies.
Binding activities of S139/1 IgA (continuous lines) and IgG (dashed lines) were tested in ELISA. Disrupted viral particles of Aichi/H3, WSN/H1, Adachi/H2, and Maryland/H13 were used as antigens. Data are mean values of duplicate wells. EC50 values calculated based on the ELISA data are shown in Table 1.
Muramatsu, M., Yoshida, R., Yokoyama, A., Miyamoto, H., Kajihara, M., Maruyama, J., ... & Takada, A. (2014). Comparison of antiviral activity between IgA and IgG specific to influenza virus hemagglutinin: increased potential of IgA for heterosubtypic immunity. PLoS One, 9(1), e85582.
Figure 3 Comparison of neutralizing activities of S139/1 IgA and IgG antibodies.
Appropriately diluted viruses were mixed with S139/1 IgA (continuous lines) or IgG (dashed lines) at the indicated dilutions. Neutralizing activities were evaluated by counting the number of plaques formed on MDCK cells. IC50 values calculated based on the neutralization curves are shown in Table 3.
Muramatsu, M., Yoshida, R., Yokoyama, A., Miyamoto, H., Kajihara, M., Maruyama, J., ... & Takada, A. (2014). Comparison of antiviral activity between IgA and IgG specific to influenza virus hemagglutinin: increased potential of IgA for heterosubtypic immunity. PLoS One, 9(1), e85582.
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• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
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• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-426 | Recombinant Anti-IAV H1N1 Antibody | ELISA, WB, FC, FuncS | IgG |
PABL-110 | Recombinant Human Anti-H1N1 Antibody (del2D1) | WB, ELISA, FuncS | IgG |
HPAB-2318LY | Human Anti-H1N1 Recombinant Antibody (HPAB-2318LY) | ELISA, Neut | Humanized IgG |
HPAB-2319LY | Human Anti-H1N1 Recombinant Antibody (HPAB-2319LY) | ELISA, Neut, FuncS | Humanized IgG |
HPAB-AP359-YC | Recombinant Mouse Anti-H1N1 Antibody (SIVHLl) | ELISA | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
NABG-074 | Recombinant Anti-H1N1 VHH Single Domain Antibody | ELISA, IHC, FC, FuncS | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-110 | Recombinant Human Anti-H1N1 Antibody scFv Fragment (del2D1) | WB, ELISA, FuncS | scFv |
HPAB-2318LY-S(P) | Human Anti-H1N1 Recombinant Antibody; scFv Fragment (HPAB-2318LY-S(P)) | ELISA, Neut | Humanized scfv |
HPAB-2319LY-S(P) | Human Anti-H1N1 Recombinant Antibody; scFv Fragment (HPAB-2319LY-S(P)) | ELISA, Neut | Humanized scfv |
HPAB-0795-FY-F(E) | Mouse Anti-H1N1 Recombinant Antibody; Fab Fragment (HPAB-0795-FY-F(E)) | E, N | Mouse Fab |
HPAB-0796-FY-F(E) | Mouse Anti-H1N1 Recombinant Antibody; Fab Fragment (HPAB-0796-FY-F(E)) | E, N | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-118-S (P) | Recombinant Mouse Anti-Influenza A Antibody scFv Fragment (S139) | WB, ELISA, IF, FuncS | scFv |
PABX-118-F (E) | Recombinant Mouse Anti-Influenza A Antibody Fab Fragment (S139) | WB, ELISA, IF, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-4205 | Hi-Affi™ Recombinant Rabbit Anti-H1N1 Monoclonal Antibody (SI283DS) | WB, ELISA, FC, IP | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-2318LY-F(E) | Human Anti-H1N1 Recombinant Antibody; Fab Fragment (HPAB-2318LY-F(E)) | ELISA, Neut | Humanized Fab |
HPAB-2319LY-F(E) | Human Anti-H1N1 Recombinant Antibody; Fab Fragment (HPAB-2319LY-F(E)) | ELISA, Neut | Humanized Fab |
HPAB-0795-FY-S(P) | Mouse Anti-H1N1 Recombinant Antibody; scFv Fragment (HPAB-0795-FY-S(P)) | E, N | Mouse scFv |
HPAB-0796-FY-S(P) | Mouse Anti-H1N1 Recombinant Antibody; scFv Fragment (HPAB-0796-FY-S(P)) | E, N | Mouse scFv |
HPAB-0797-FY-S(P) | Mouse Anti-H1N1 Recombinant Antibody; scFv Fragment (HPAB-0797-FY-S(P)) | E | Mouse scFv |
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