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Anti-Integrin αvβ5 Therapeutic Antibody (TAB-448CL)

Recombinant Human monoclonal antibody expressed in CHO binding to Human Integrin αvβ5. This is a function-blocking antibody against the integrin αvβ5 prevented development of lung vascular permeability in two different models of acute lung injury (ALI). The integrin αvβ5 can used as a central regulator of increased pulmonary vascular permeability and a potentially attractive therapeutic target in ALI.      

Specifications
Host
Human
Derivation
Mouse
Type
Antibody
Species Reactivity
Human
Related Disease
Sepsis
Target
Alternative Names
Integrin αvβ5; Integrin alphaV beta5; Integrin α5β5

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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