Anti-human Integrin αvβ6 Recombinant Antibody (sc 188) (TAB-765LC) (CAT#: TAB-765LC)

Recombinant monoclonal antibody sc 188 is a human monoclonal antibody that specifically binds to human αvβ6 integrin and can be potentially used in the treatment of arthritis, atherosclerosis and allergic conjunctivitis.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Datasheet
  • MSDS
  • COA
Inhib

Figure 1  is a line graph showing the ability of the purified monoclonal antibodies to bind to αVβό and block its binding to a GST-LAP peptide.

Figure 1 is a line graph showing the ability of the purified monoclonal antibodies to bind to αVβό and block its binding to a GST-LAP peptide.

Cyt

Figure 2 bar graphs showing the ability of the purified monoclonal antibodies to mediate complement-dependent cytotoxicity in 293 cells stably expressing αVβό integrin.

Figure 2 bar graphs showing the ability of the purified monoclonal antibodies to mediate complement-dependent cytotoxicity in 293 cells stably expressing αVβό integrin.

FuncS

Figure 3 is a bar graph showing the ability of antibodies 264RAD. 133 and 188 SDM to inhibit tumour growth using the Detroit-562 nasophayngeal cell line.

Figure 3 is a bar graph showing the ability of antibodies 264RAD. 133 and 188 SDM to inhibit tumour growth using the Detroit-562 nasophayngeal cell line.


Specifications

  • Immunogen
  • Human integrin αvβ6
  • Host Species
  • Human
  • Type
  • Human antibody
  • Specificity
  • Human
  • Species Reactivity
  • Macaque
  • Clone
  • sc 188
  • Applications
  • Cyt, FuncS, Inhib
  • Related Disease
  • Arthritis, atherosclerosis and allergic conjunctivitis

Applications

  • Application Notes
  • This antibody has been reported for use in Cytotoxicity, Functional Assay, Inhibition.

Target

  • Alternative Names
  • Integrin αvβ6; Integrin alphaV beta6

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone sc 188"

See other products for "Integrin αvβ6"

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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