This immunotoxin was achieved by conjugating/fusing the Anti-KDR monoclonal antibody to Pseudomonas exotoxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to tumor cells. Once bind, the toxin enters cells by receptor-mediated endocytosis. Then PE cleaved fragments the size of Mr 37000 and 27000, the large fragment and finally into the Golgi and elongation factor 2 (EM) combining it glycosylation inactivation, inhibition of protein synthesis, leading to apoptosis. It was designed for inhibiting tumor angiogenesis.
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• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
IAB-B066(A) | Recombinant Anti-human KDR Intrabody [(D-Arg)9] | FC, IF, FuncS | scFv-(D-Arg)9 |
IAB-B066(G) | Recombinant Anti-human KDR Intrabody [+36 GFP] | CO-IP, FuncS | scFv-(+36GFP) |
IAB-B066(T) | Recombinant Anti-human KDR Intrabody [Tat] | IF, ELISA, FuncS | scFv-Tat |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-202 | Humanized Anti-KDR Recombinant Antibody (clone Alacizumab); di - Fab' Fragment | IF, IP, Neut, FuncS, ELISA, FC, ICC | Humanized (from mouse) di - Fab' |
TAB-411CQ | Anti-Human KDR Recombinant Antibody (HLX06) | ELISA | Humanized antibody |
TAB-411CQ-S(P) | Anti-Human KDR Recombinant Antibody scFv Fragment (HLX06) | ELISA | Humanized antibody |
TAB-411CQ-F(E) | Anti-Human KDR Recombinant Antibody Fab Fragment (HLX06) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0298CL | Human Anti-KDR Recombinant Antibody (TAB-0298CL) | WB, FC, ELISA, Inhib, Neut, FuncS | Human IgG |
TAB-0299CL | Human Anti-KDR Recombinant Antibody (TAB-0299CL) | WB, FC, Inhib, Neut | Human IgG |
TAB-0298CL-F(E) | Human Anti-KDR Recombinant Antibody; Fab Fragment (TAB-0298CL-F(E)) | FC, ELISA, Inhib, Neut, FuncS | Human Fab |
TAB-0299CL-F(E) | Human Anti-KDR Recombinant Antibody; Fab Fragment (TAB-0299CL-F(E)) | WB, FC, Inhib, Neut | Human Fab |
TAB-322CQ | Anti-Human KDR Recombinant Antibody (AK404R) | ELISA, WB, Inhib | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-326CQ | Rat Anti-Kdr Recombinant Antibody (TAB-326CQ) | ELISA, IHC | Rat IgG |
TAB-331CQ | Anti-Human KDR Recombinant Antibody (6.64) | IHC, ELISA | Mouse IgG1 |
TAB-326CQ-S(P) | Rat Anti-Kdr Recombinant Antibody; scFv Fragment (TAB-326CQ-S(P)) | ELISA, FC, WB | Rat scFv |
TAB-331CQ-S(P) | Anti-Human KDR Recombinant Antibody scFv Fragment (6.64) | ELISA, FC, IHC | |
TAB-332CQ-S(P) | Anti-Human KDR Recombinant Antibody scFv Fragment (4.13) | ELISA, FC, IHC |
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0624MZ | Chicken Anti-VEGFR-2 Polyclonal IgY | IHC, WB | Chicken antibody |
BRD-0709MZ | Chicken Anti-KDR Polyclonal IgY | WB | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1619CQ | Recombinant Mouse Anti-KDR Antibody (23B31) | WB, IP, FC, Neut | |
NEUT-1620CQ | Recombinant Rat Anti-Kdr Antibody (CBL840) | ELISA(Cap), Neut | IgG2a |
NEUT-1621CQ | Recombinant Rat Anti-Kdr Antibody (CBL880) | Neut, WB | IgG2 |
NEUT-1622CQ | Recombinant Mouse Anti-KDR Antibody (6B11) | WB, Neut | IgG1 |
NEUT-1623CQ | Recombinant Mouse Anti-KDR Antibody (CBL505) | FC, CyTOF, Neut | IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1927 | Hi-Affi™ Recombinant Rabbit Anti-KDR Monoclonal Antibody (DS1927AB) | IHC-P | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0097-YC-F(E) | Rabbit Anti-KDR Recombinant Antibody; Fab Fragment (HPAB-0097-YC-F(E)) | ELISA, FuncS | Rabbit Fab |
HPAB-0098-YC-F(E) | Rabbit Anti-KDR Recombinant Antibody; Fab Fragment (HPAB-0098-YC-F(E)) | ELISA, FuncS | Rabbit Fab |
HPAB-0099-YC-F(E) | Rabbit Anti-KDR Recombinant Antibody; Fab Fragment (HPAB-0099-YC-F(E)) | ELISA, FuncS | Rabbit Fab |
HPAB-1279-FY-S(P) | Mouse Anti-KDR Recombinant Antibody; scFv Fragment (HPAB-1279-FY-S(P)) | ELISA, FC, Inhib | Mouse scFv |
HPAB-1280-FY-S(P) | Mouse Anti-KDR Recombinant Antibody; scFv Fragment (HPAB-1280-FY-S(P)) | ELISA, FC, Inhib | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-079 | Afuco™ Anti-KDR ADCC Recombinant Antibody (Ramucirumab), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0246-WJ-S(P) | Human Anti-KDR Recombinant Antibody; scFv Fragment (HPAB-0246-WJ-S(P)) | ELISA, IF, FC | Human scFv |
HPAB-0016-YJ-S(P) | Mouse Anti-KDR Recombinant Antibody; scFv Fragment (HPAB-0016-YJ-S(P)) | RIA, ELISA | Mouse scFv |
HPAB-0567-WJ-S(P) | Human Anti-KDR Recombinant Antibody; scFv Fragment (HPAB-0567-WJ-S(P)) | ELISA, FC, WB | Human scFv |
HPAB-0775-YJ-S(P) | Rabbit Anti-KDR Recombinant Antibody (1V09); scFv Fragment | ELISA, FC | Rabbit scFv |
HPAB-0776-YJ-S(P) | Rabbit Anti-KDR Recombinant Antibody (2V05); scFv Fragment | ELISA, FC | Rabbit scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-M0126-YC | Human Anti-KDR Recombinant Antibody (clone RD) | ELISA | Human IgG |
HPAB-M0127-YC | Human Anti-KDR Recombinant Antibody (clone PCABHL3) | ELISA, Inhib | Humanized IgG |
HPAB-M0128-YC | Human Anti-KDR Recombinant Antibody (clone PCABHL5) | ELISA, Inhib | Humanized IgG |
HPAB-M0129-YC | Human Anti-KDR Recombinant Antibody (clone PCABHL7) | ELISA, Inhib | Humanized IgG |
HPAB-M0130-YC | Human Anti-KDR Recombinant Antibody (clone H15PCABL) | ELISA, Inhib | Humanized IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0298-YJ-VHH | Recombinant Human Anti-KDR Nano Antibody (NTV1) | Inhib | Human VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-YF304 | A*24:02/Human VEGFR (SYGVLLWEI) MHC Monomer | MHC Multimer | |
MHC-YF772 | H-2Db/Human VEGFR2/KDR fragment 1 (FSNSTNDILI) MHC Pentamer | FCM |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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