Anti-Human KDR Recombinant Antibody (AK404R) (CAT#: TAB-322CQ)
Recombinant monoclonal antibody AK404R targets the outer 3 district KDR3 of human VEGFR2. This human antibody can suppress the inductive huve cell proliferation of VEGF institute external, and can be potentially used in the treatment of solid tumors.
Specific Inquiry
ELISA
Figure 1 Monoclonal phage ELISA to immobilized KDR3 (n = 3).
The illustrated scFvs exhibited high absorbance at OD450/650 in ELISA assay, indicating preferential phages with high affinity were successfully enriched. The experiment was repeated three times.
Zhang, J., Li, H., Wang, X., Qi, H., Miao, X., Zhang, T., ... & Wang, M. (2012). Phage‐derived fully human antibody scFv fragment directed against human vascular endothelial growth factor receptor 2 blocked its interaction with VEGF. Biotechnology progress, 28(4), 981-989.
Inhib
Figure 2 Inhibition on VEGF stimulated proliferation of HUVECs.
The proliferative ability of HUVECs decreased gradually with the incubation of AK404R from 0.75 nM to 7.5 nM. The calculated concentration for 50% cell growth inhibition was 5 nM.
Zhang, J., Li, H., Wang, X., Qi, H., Miao, X., Zhang, T., ... & Wang, M. (2012). Phage‐derived fully human antibody scFv fragment directed against human vascular endothelial growth factor receptor 2 blocked its interaction with VEGF. Biotechnology progress, 28(4), 981-989.
Specifications
- Host Species
- Human
- Type
- Human antibody
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- AK404R
- Applications
- ELISA, WB, Inhib
- Related Disease
- Solid tumors
Applications
- Application Notes
- This antibody has been tested for use in ELISA, Western Blot, Inhibition. The biological activity of AK404R is by the inhibiting rate evaluation of cell growth.
Target
- Alternative Names
- KDR; kinase insert domain receptor; FLK1; CD309; VEGFR; VEGFR2; vascular endothelial growth factor receptor 2; soluble VEGFR2; fetal liver kinase 1; fetal liver kinase-1; protein-tyrosine kinase receptor Flk-1; tyrosine kinase growth factor receptor; kinase insert domain receptor (a type III receptor tyrosine kinase)
- Gene ID
- 3791
- UniProt ID
- P35968
- Long Name
- Kinase insert domain receptor
Recommended Products
Isotype Control
Secondary Antibody
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone AK404R"
See other products for "KDR"
Intrabody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B066(A) | Recombinant Anti-human KDR Intrabody [(D-Arg)9] | FC, IF, FuncS | scFv-(D-Arg)9 |
| IAB-B066(G) | Recombinant Anti-human KDR Intrabody [+36 GFP] | CO-IP, FuncS | scFv-(+36GFP) |
| IAB-B066(T) | Recombinant Anti-human KDR Intrabody [Tat] | IF, ELISA, FuncS | scFv-Tat |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-202 | Humanized Anti-KDR Recombinant Antibody (clone Alacizumab); di - Fab' Fragment | IF, IP, Neut, FuncS, ELISA, FC, ICC | Humanized (from mouse) di - Fab' |
| TAB-411CQ | Anti-Human KDR Recombinant Antibody (HLX06) | ELISA | Humanized antibody |
| TAB-411CQ-S(P) | Anti-Human KDR Recombinant Antibody scFv Fragment (HLX06) | ELISA | Humanized antibody |
| TAB-411CQ-F(E) | Anti-Human KDR Recombinant Antibody Fab Fragment (HLX06) | ELISA | Humanized antibody |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G047E | Anti-KDR immunotoxin (IgG1)-PE | Cytotoxicity assay, Function study |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-204 | Mouse Anti-KDR Recombinant Antibody (clone mAb6.64); scFv Fragment | Neut, Block | Mouse scFv |
| HPAB-0097-YC-S(P) | Rabbit Anti-KDR Recombinant Antibody; scFv Fragment (HPAB-0097-YC-S(P)) | ELISA, FuncS | Rabbit scFv |
| HPAB-0098-YC-S(P) | Rabbit Anti-KDR Recombinant Antibody; scFv Fragment (HPAB-0098-YC-S(P)) | ELISA, FuncS | Rabbit scFv |
| HPAB-0502-YJ-S(P) | Human Anti-KDR Recombinant Antibody (clone 1); scFv Fragment | ELISA, FC | Human scFv |
| HPAB-0503-YJ-S(P) | Human Anti-KDR Recombinant Antibody (clone 6); scFv Fragment | ELISA, FC | Human scFv |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-326CQ | Rat Anti-Kdr Recombinant Antibody (TAB-326CQ) | ELISA, IHC | Rat IgG |
| TAB-331CQ | Anti-Human KDR Recombinant Antibody (6.64) | IHC, ELISA | Mouse IgG1 |
| TAB-326CQ-S(P) | Rat Anti-Kdr Recombinant Antibody; scFv Fragment (TAB-326CQ-S(P)) | ELISA, FC, WB | Rat scFv |
| TAB-331CQ-S(P) | Anti-Human KDR Recombinant Antibody scFv Fragment (6.64) | ELISA, FC, IHC | |
| TAB-332CQ-S(P) | Anti-Human KDR Recombinant Antibody scFv Fragment (4.13) | ELISA, FC, IHC |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-322CQ-S(P) | Anti-Human KDR Recombinant Antibody scFv Fragment (AK404R) | ELISA, WB | Human antibody |
| TAB-325CQ-S(P) | Human Anti-KDR Recombinant Antibody; scFv Fragment (TAB-325CQ-S(P)) | ELISA, FC | Human scFv |
| TAB-329CQ-S(P) | Human Anti-KDR Recombinant Antibody; scFv Fragment (TAB-329CQ-S(P)) | ELISA, WB, Neut | Human scFv |
| TAB-330CQ-S(P) | Mouse Anti-KDR Recombinant Antibody; scFv Fragment (TAB-330CQ-S(P)) | ELISA, WB, Neut | Mouse scFv |
| TAB-333CQ-S(P) | Human Anti-KDR Recombinant Antibody; scFv Fragment (TAB-333CQ-S(P)) | ELISA, FC | Human scFv |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0624MZ | Chicken Anti-VEGFR-2 Polyclonal IgY | IHC, WB | Chicken antibody |
| BRD-0709MZ | Chicken Anti-KDR Polyclonal IgY | WB | Chicken antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1619CQ | Recombinant Mouse Anti-KDR Antibody (23B31) | WB, IP, FC, Neut | |
| NEUT-1620CQ | Recombinant Rat Anti-Kdr Antibody (CBL840) | ELISA(Cap), Neut | IgG2a |
| NEUT-1621CQ | Recombinant Rat Anti-Kdr Antibody (CBL880) | Neut, WB | IgG2 |
| NEUT-1622CQ | Recombinant Mouse Anti-KDR Antibody (6B11) | WB, Neut | IgG1 |
| NEUT-1623CQ | Recombinant Mouse Anti-KDR Antibody (CBL505) | FC, CyTOF, Neut | IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1927 | Hi-Affi™ Recombinant Rabbit Anti-KDR Monoclonal Antibody (DS1927AB) | IHC-P | IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0097-YC-F(E) | Rabbit Anti-KDR Recombinant Antibody; Fab Fragment (HPAB-0097-YC-F(E)) | ELISA, FuncS | Rabbit Fab |
| HPAB-0098-YC-F(E) | Rabbit Anti-KDR Recombinant Antibody; Fab Fragment (HPAB-0098-YC-F(E)) | ELISA, FuncS | Rabbit Fab |
| HPAB-0099-YC-F(E) | Rabbit Anti-KDR Recombinant Antibody; Fab Fragment (HPAB-0099-YC-F(E)) | ELISA, FuncS | Rabbit Fab |
| HPAB-M0126-YC-F(E) | Human Anti-KDR Recombinant Antibody (clone RD); Fab Fragment | ELISA | Human Fab |
| HPAB-M0127-YC-F(E) | Human Anti-KDR Recombinant Antibody (clone PCABHL3); Fab Fragment | ELISA, Inhib | Humanized Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1580-CN | Recombinant Rabbit Anti-KDR Monoclonal Antibody (SU03-42) | WB, IF, IHC, IP | Rabbit IgG |
| HPAB-0251-FY | Human Anti-KDR Recombinant Antibody (clone 043HAb-1) | ELISA | Human IgG1 |
| HPAB-0252-FY | Human Anti-KDR Recombinant Antibody (clone 043HAb-2) | ELISA | Human IgG1 |
| HPAB-0253-FY | Human Anti-KDR Recombinant Antibody (clone 043HAb-3) | ELISA | Human IgG1 |
| HPAB-0254-FY | Human Anti-KDR Recombinant Antibody (clone 043HAb-4) | ELISA | Human IgG1 |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-079 | Afuco™ Anti-KDR ADCC Recombinant Antibody (Ramucirumab), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0298-YJ-VHH | Recombinant Human Anti-KDR Nano Antibody (NTV1) | Inhib | Human VHH |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF304 | A*24:02/Human VEGFR (SYGVLLWEI) MHC Monomer | MHC Multimer | |
| MHC-YF772 | H-2Db/Human VEGFR2/KDR fragment 1 (FSNSTNDILI) MHC Pentamer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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