This recombinant monoclonal antibody L1-9.3 is a mouse monoclonal antibody that specifically binds to human L1CAM. It is recommended for the detection of human L1CAM by ELISA, WB, IHC, and FC.
Figure 1 Characterization of novel mAb to L1.
Western blot analysis of cell lysate from the indicated cells.
Wolterink, S., Moldenhauer, G., Fogel, M., Kiefel, H., Pfeifer, M., Lüttgau, S., ... & Altevogt, P. (2010). Therapeutic antibodies to human L1CAM: functional characterization and application in a mouse model for ovarian carcinoma. Cancer research, 70(6), 2504-2515.
Figure 2 Characterization of novel mAb to L1.
Immunohistochemical staining of human ovarian carcinoma tissues with anti-L1 mAbs.
Wolterink, S., Moldenhauer, G., Fogel, M., Kiefel, H., Pfeifer, M., Lüttgau, S., ... & Altevogt, P. (2010). Therapeutic antibodies to human L1CAM: functional characterization and application in a mouse model for ovarian carcinoma. Cancer research, 70(6), 2504-2515.
Figure 3 Characterization of novel mAb to L1.
The purified Fc protein was coated, and mAb binding was analyzed by ELISA.
Wolterink, S., Moldenhauer, G., Fogel, M., Kiefel, H., Pfeifer, M., Lüttgau, S., ... & Altevogt, P. (2010). Therapeutic antibodies to human L1CAM: functional characterization and application in a mouse model for ovarian carcinoma. Cancer research, 70(6), 2504-2515.
Figure 4 Anti-L1 mAbs to the intracellular but not extracellular domain cross-react with human CHL1.
Purified CHL1-Fc was tested in ELISA for cross-reactivity with anti-L1 mAbs. L1-Fc was used as positive control and POX-conjugated goat anti-human Fc for equal coating.
Wolterink, S., Moldenhauer, G., Fogel, M., Kiefel, H., Pfeifer, M., Lüttgau, S., ... & Altevogt, P. (2010). Therapeutic antibodies to human L1CAM: functional characterization and application in a mouse model for ovarian carcinoma. Cancer research, 70(6), 2504-2515.
Figure 5 Characterization of humanized L1-9.3 mAb.
Wolterink, S., Moldenhauer, G., Fogel, M., Kiefel, H., Pfeifer, M., Lüttgau, S., ... & Altevogt, P. (2010). Therapeutic antibodies to human L1CAM: functional characterization and application in a mouse model for ovarian carcinoma. Cancer research, 70(6), 2504-2515.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1178z | Mouse Anti-L1CAM Recombinant Antibody (clone 8A2) | WB, FC, ICC, IF, IHC, IP | Mouse IgG1 |
MOB-0910CT | Recombinant Mouse anti-Human L1CAM Monoclonal antibody (6H4) | FC | |
HPAB-0398-CN | Mouse Anti-L1CAM Recombinant Antibody (HPAB-0398-CN) | WB, ELISA, FC, IHC | Mouse IgG1 |
MRO-2060-CN | Rabbit Anti-L1CAM Polyclonal Antibody (MRO-2060-CN) | WB, IF, IHC, FC | Rabbit IgG |
VS3-CJ72 | Mouse Anti-L1CAM Recombinant Antibody (VS3-CJ72) | WB, ELISA | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0635CL | Human Anti-L1CAM Recombinant Antibody (TAB-0635CL) | WB, IF, IHC, PK, ELISA, FC | Human antibody |
TAB-0635CL-S(P) | Human Anti-L1CAM Recombinant Antibody; scFv Fragment (TAB-0635CL-S(P)) | ELISA, FC | Human scFv |
TAB-0635CL-F(E) | Human Anti-L1CAM Recombinant Antibody; Fab Fragment (TAB-0635CL-F(E)) | ELISA, FC | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0636CL-S(P) | Anti-Human L1CAM Recombinant Antibody scFv Fragment (L1-9.3) | WB, FC | |
TAB-0636CL-F(E) | Anti-Human L1CAM Recombinant Antibody Fab Fragment (L1-9.3) | WB, FC |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1999 | Hi-Affi™ Recombinant Rabbit Anti-L1CAM Monoclonal Antibody (DS1999AB) | ELISA, WB | IgG |
MOR-4297 | Hi-Affi™ Recombinant Rabbit Anti-L1CAM Monoclonal Antibody (SI384DS) | FC | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0191-YC-S(P) | Human Anti-L1CAM Recombinant Antibody (clone G6); scFv Fragment | ELISA, IF, WB | Human scFv |
FAMAB-0192-YC-S(P) | Human Anti-L1CAM Recombinant Antibody (clone H2); scFv Fragment | ELISA, IF, WB | Human scFv |
HPAB-0827-CN-S(P) | Human Anti-L1CAM Recombinant Antibody; scFv Fragment (HPAB-0827-CN-S(P)) | WB, ELISA, IHC, FC | Human scFv |
HPAB-0828-CN-S(P) | Human Anti-L1CAM Recombinant Antibody; scFv Fragment (HPAB-0828-CN-S(P)) | WB, ELISA, IHC, FC | Human scFv |
HPAB-J0160-YC-S(P) | Human Anti-L1CAM Recombinant Antibody (clone Ab4); scFv Fragment | ELISA, FC, WB, FuncS | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0191-YC-F(E) | Human Anti-L1CAM Recombinant Antibody (clone G6); Fab Fragment | ELISA, IF, WB | Human Fab |
FAMAB-0192-YC-F(E) | Human Anti-L1CAM Recombinant Antibody (clone H2); Fab Fragment | ELISA, IF, WB | Human Fab |
HPAB-0827-CN-F(E) | Human Anti-L1CAM Recombinant Antibody; Fab Fragment (HPAB-0827-CN-F(E)) | WB, ELISA, IHC, FC | Human Fab |
HPAB-0828-CN-F(E) | Human Anti-L1CAM Recombinant Antibody; Fab Fragment (HPAB-0828-CN-F(E)) | WB, ELISA, IHC, FC | Human Fab |
HPAB-J0160-YC-F(E) | Human Anti-L1CAM Recombinant Antibody (clone Ab4); Fab Fragment | ELISA, FC, WB, FuncS | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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