Anti-Human LAG3 Recombinant Antibody Fab Fragment (TSR-033) (CAT#: TAB-0367CL-F(E))
The the LAG-3-specific antibody anti-LAG-3 antibody demonstrate potent and durable anti-tumor activity in syngeneic tumor models and therefore can be used for immunotherapy.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human tonsil
(High expression. RNA expression: 10.9 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13967/30401_A_4_8_val_selected.jpg
(High expression. RNA expression: 10.9 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13967/30401_A_4_8_val_selected.jpg
Figure 2 IHC staining of human cerebral cortex
(Low expression. RNA expression: 0.7 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13967/30401_B_9_5_val_selected.jpg
(Low expression. RNA expression: 0.7 nTPM)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13967/30401_B_9_5_val_selected.jpg
Figure 3 Colon
(Glandular cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13967/30401_A_8_3.jpg
(Glandular cells
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13967/30401_A_8_3.jpg
Figure 4 Liver
(Hepatocytes
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2301/5962_A_7_4.jpg
(Hepatocytes
Staining: Not detected
Intensity: Weak
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2301/5962_A_7_4.jpg
Figure 5 Testis
(Leydig cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2301/5962_A_4_6.jpg
(Leydig cells
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2301/5962_A_4_6.jpg
Figure 6 Lymph node
(Germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13967/30401_A_7_8.jpg
(Germinal center cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/13967/30401_A_7_8.jpg
Figure 7 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000089692-LAG3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000089692-LAG3
Specifications
- Immunogen
- Human LAG-3 ECD (for panning)
- Host Species
- Human
- Type
- Human antibody
- Specificity
- Human
- Clone
- TSR-033
- Related Disease
- Tumor
Target
- Alternative Names
- LAG3; lymphocyte-activation gene 3; CD223; lymphocyte activation gene 3 protein
- Gene ID
- 3902
- UniProt ID
- P18627
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0367CL | Anti-Human LAG3 Recombinant Antibody (TSR-033) | FC, FuncS, Block | Human antibody |
| TAB-0367CL-S(P) | Anti-Human LAG3 Recombinant Antibody scFv Fragment (TSR-033) | ELISA, WB | Human antibody |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0638CL | Mouse Anti-LAG3 Recombinant Antibody (TAB-0638CL) | ELISA, IHC | Mouse IgG |
| TAB-0639CL | Mouse Anti-LAG3 Recombinant Antibody (TAB-0639CL) | ELISA, IHC | Mouse IgG2a |
| TAB-0640CL | Mouse Anti-LAG3 Recombinant Antibody (TAB-0640CL) | ELISA, IHC | Mouse IgG1 |
| TAB-0641CL | Mouse Anti-LAG3 Recombinant Antibody (TAB-0641CL) | ELISA, IHC | Mouse IgG2b |
| TAB-0638CL-S(P) | Mouse Anti-LAG3 Recombinant Antibody; scFv Fragment (TAB-0638CL-S(P)) | ELISA, IHC | Mouse scFv |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0642CL | Human Anti-LAG3 Recombinant Antibody (TAB-0642CL) | ELISA, IHC | Humanized IgG4 |
| TAB-0642CL-S(P) | Human Anti-LAG3 Recombinant Antibody; scFv Fragment (TAB-0642CL-S(P)) | ELISA, IHC | Humanized scFv |
| TAB-0642CL-F(E) | Human Anti-LAG3 Recombinant Antibody; Fab Fragment (TAB-0642CL-F(E)) | ELISA, IHC | Humanized Fab |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1675CQ | Recombinant Mouse Anti-LAG3 Antibody (11E3) | WB, Neut, ELISA, IF, IHC, IP | IgG1 |
| NEUT-1676CQ | Recombinant Rat Anti-Lag3 Antibody (C9B7W) | ELISA, FuncS, FC, IP, Neut | IgG1, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2002 | Hi-Affi™ Recombinant Rabbit Anti-LAG3 Monoclonal Antibody (DS2002AB) | IHC-P, FC | IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0690-CN-F(E) | Human Anti-LAG3 Recombinant Antibody; Fab Fragment (HPAB-0690-CN-F(E)) | WB, ELISA, FC, IHC | Human Fab |
| HPAB-0691-CN-F(E) | Human Anti-LAG3 Recombinant Antibody; Fab Fragment (HPAB-0691-CN-F(E)) | WB, ELISA, FC, IHC | Human Fab |
| HPAB-0692-CN-F(E) | Human Anti-LAG3 Recombinant Antibody; Fab Fragment (HPAB-0692-CN-F(E)) | WB, ELISA, FC, IHC | Human Fab |
| HPAB-0693-CN-F(E) | Human Anti-LAG3 Recombinant Antibody; Fab Fragment (HPAB-0693-CN-F(E)) | WB, ELISA, FC, IHC | Human Fab |
| HPAB-2358LY-F(E) | Human Anti-LAG3 Recombinant Antibody; Fab Fragment (HPAB-2358LY-F(E)) | ELISA | Humanized Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2358LY | Human Anti-LAG3 Recombinant Antibody (HPAB-2358LY) | ELISA, FuncS | Humanized IgG |
| HPAB-2359LY | Human Anti-LAG3 Recombinant Antibody (HPAB-2359LY) | ELISA, FuncS | Humanized IgG |
| HPAB-2360LY | Human Anti-LAG3 Recombinant Antibody (HPAB-2360LY) | ELISA, FuncS | Humanized IgG |
| HPAB-2361LY | Human Anti-LAG3 Recombinant Antibody (HPAB-2361LY) | ELISA, FuncS | Humanized IgG |
| HPAB-2362LY | Human Anti-LAG3 Recombinant Antibody (HPAB-2362LY) | ELISA, FuncS | Humanized IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-2851LY-S(P) | Human Anti-LAG3 Recombinant Antibody; scFv Fragment (HPAB-2851LY-S(P)) | ELISA | Human scFv |
| HPAB-0388-YJ-S(P) | Mouse Anti-LAG3 Recombinant Antibody; scFv Fragment (HPAB-0388-YJ-S(P)) | FC, FuncS | Mouse scFv |
| HPAB-0389-YJ-S(P) | Human Anti-LAG3 Recombinant Antibody; scFv Fragment (HPAB-0389-YJ-S(P)) | FC, FuncS | Humanized scFv |
| HPAB-0771YY-S(P) | Human Anti-LAG3 Recombinant Antibody; scFv Fragment (HPAB-0771YY-S(P)) | Inhib, Cyt | Human scFv |
| HPAB-0787YY-S(P) | Human Anti-LAG3 Recombinant Antibody; scFv Fragment (HPAB-0787YY-S(P)) | Inhib, Cyt | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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