Afuco™ Anti-Human LCP1 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-467CL)
Anti-LCP1 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The antibodies, especially camelid antibodies, binding to the tandem actin binding domain in L-plastin, but not to the single actin binding domains. It further relates to the use of those antibodies to limit cell invasion and metastasis in cancer.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane, cytosol & actin filaments.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19493/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane, cytosol & actin filaments.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19493/if_selected.jpg
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/20673/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/20673/if_selected.jpg
Figure 3 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19493/277_F2_1_blue_red_green.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19493/277_F2_1_blue_red_green.jpg
Figure 4 Colon
(Mucosal lymphoid cells
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19493/46660_A_8_3.jpg
(Mucosal lymphoid cells
Staining:High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19493/46660_A_8_3.jpg
Figure 5 Lymph node
(Germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19493/46660_A_9_8.jpg
(Germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19493/46660_A_9_8.jpg
Figure 6 RNA cell line category: Cell line enhanced (Daudi, HDLM-2, HL-60, HMC-1, JURKAT, NB-4, THP-1, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000136167-LCP1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000136167-LCP1
Specifications
- Host Species
- Camelid
- Derivation
- Camelid
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >95% by HPLC
- Storage
- Short term: store at 4°C (over 6 months), long term: -20°C or -80°C.
Target
- Alternative Names
- LCP1; lymphocyte cytosolic protein 1 (L-plastin); LPL; CP64; PLS2; LC64P; HEL-S-37; L-PLASTIN; plastin-2; LCP-1; plastin 2; epididymis secretory protein Li 37; Lymphocyte cytosolic protein-1 (plasmin); bA139H14.1 (lymphocyte cytosolic protein 1 (L-plastin)); L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (LC64P)
- Gene ID
- 3936
- UniProt ID
- A0A024RDT4
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "LCP1"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-801-sdAb | Recombinant Anti-human LCP1 VHH Single Domain Antibody | WB, IP, ICC, FC, FA | Llama VHH |
| TAB-0071CL-VHH | Anti-Human LCP1 VHH Single Domain Antibody (Nb2) | ELISA, FC | Single domain antibody |
| TAB-0072CL-VHH | Anti-Human LCP1 VHH Single Domain Antibody (Nb9) | ELISA, FC | Single domain antibody |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1349z | Mouse Anti-LCP1 Recombinant Antibody (clone 28B11) | WB, IP, IF, IHC, ELISA | Mouse IgG1, κ |
| MOB-1614CT | Recombinant Mouse anti-Human LCP1 Monoclonal antibody (MQM5B.2) | ICC/IF, IHC-Fr, IP, WB | |
| VS3-WK384 | Rabbit Anti-LCP1 Recombinant Antibody (clone JE48-95) | WB, IHC, FC | Rabbit IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2026 | Hi-Affi™ Recombinant Rabbit Anti-LCP1 Monoclonal Antibody (DS2026AB) | FC, ICC, IHC-P, IP, WB | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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