Products

Anti-LRP6 Fab (DMS10031) (TAB-0348CL-F(E))

The anti-LRP6 antibody specifically bind to low-density lipoprotein receptor-related protein 6 which acts functionally as Wnt ligand co-receptor. By inhibiting the binding of Wnt ligands to the LRP6 receptor, Thus the antibody can be used in the treatment of diseases in which the abnormal wnt signaling is implicated such as breast cancer, prostate cancer and pancreatic cancer.      

Specifications
Host
Mouse
Type
Chimeric (mouse/human)
Specificity
Human
Species Reactivity
DMS10031 showed Cross-reactivity to cynomolgous LRP6 while no Cross-reactivity was identified to mouse LRP6
Clone
DMS10031
Related Disease
Breast Cancer, Prostate Cancer, Pancreatic Cancer
Target
Alternative Names
LRP6; low density lipoprotein receptor-related protein 6; ADCAD2; low-density lipoprotein receptor-related protein 6; LRP-6
Entrez Gene ID
4040
UniProt ID
O75581

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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