Afuco™ Anti-Human MMP13 ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-510CL)
Anti-MMP13 ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. The antibodies directed to the antigen MMP-13 are used for the treatment of diseases associated with the activity and/or overproduction of MMP-13. MMP-13 is expressed at elevated levels in cancers, degenerative bone diseases, and cardiovascular diseases. Inhibition of the biological activity of MMP-13 can delay the progression of symptoms caused by such diseases or conditions and other desired effects.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(Glial cells Staining: Not detected Neuronal cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2742/166624_B_8_5.jpg
(Glial cells Staining: Not detected Neuronal cells Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2742/166624_B_8_5.jpg
Figure 2 Liver
(Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2742/166624_A_7_4.jpg
(Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2742/166624_A_7_4.jpg
Figure 3 Kidney
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2742/166624_A_9_5.jpg
(Cells in tubules Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2742/166624_A_9_5.jpg
Figure 4 Testis
(Cells in seminiferous ducts Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2742/166624_A_5_6.jpg
(Cells in seminiferous ducts Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2742/166624_A_5_6.jpg
Figure 5 RNA cell line category: Group enriched (HaCaT, PC-3)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000137745-MMP13
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000137745-MMP13
Specifications
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer; Degenerative Bone Diseases; Cardiovascular Disease
Product Property
- Purity
- >95% as judged by SDS-polyacrylamide gel electrophoresis
- Storage
- 4 °C, -20°C if preferred
Target
- Alternative Names
- MMP13; matrix metallopeptidase 13 (collagenase 3); CLG3; MANDP1; MMP-13; collagenase 3; matrix metalloproteinase 13 (collagenase 3)
- Gene ID
- 4322
- UniProt ID
- P45452
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "MMP13"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2081z | Mouse Anti-MMP13 Recombinant Antibody (clone 19A7) | WB, ICC, IF, IHC | Mouse IgG2a |
| MOB-1941MZ | Recombinant Mouse Anti-Rat MMP13 Antibody (clone MJQDP JJE2), Biotin-Conjugated | ICC/IF, IP, WB | Mouse antibody |
| MRO-1009-CN | Recombinant Rabbit Anti-MMP13 Monoclonal Antibody (JF0893) | WB, IF, IHC, FC | Rabbit IgG |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0819CL | Anti-Human MMP13 Recombinant Antibody (14D10) | Inhib, ELISA | |
| TAB-0819CL-S(P) | Anti-Human MMP13 Recombinant Antibody scFv Fragment (14D10) | ELISA | |
| TAB-0819CL-F(E) | Anti-Human MMP13 Recombinant Antibody Fab Fragment (14D10) | ELISA |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0820CL | Human Anti-MMP13 Recombinant Antibody (TAB-0820CL) | ELISA, IHC | Human IgG |
| TAB-0820CL-S(P) | Human Anti-MMP13 Recombinant Antibody; scFv Fragment (TAB-0820CL-S(P)) | ELISA, IHC | Human scFv |
| TAB-0821CL-S(P) | Human Anti-MMP13 Recombinant Antibody; scFv Fragment (TAB-0821CL-S(P)) | ELISA, IHC | Human scFv |
| TAB-0820CL-F(E) | Human Anti-MMP13 Recombinant Antibody; Fab Fragment (TAB-0820CL-F(E)) | ELISA, IHC | Human Fab |
| TAB-0821CL-F(E) | Human Anti-MMP13 Recombinant Antibody; Fab Fragment (TAB-0821CL-F(E)) | ELISA, IHC | Human Fab |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0369MZ | Chicken Anti-MMP13 Polyclonal IgY | WB | Chicken antibody |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2250 | Hi-Affi™ Recombinant Rabbit Anti-MMP13 Monoclonal Antibody (DS2250AB) | WB | IgG |
| MOR-4649 | Hi-Affi™ Recombinant Rabbit Anti-MMP13 Monoclonal Antibody (TH162DS) | WB, IF, ICC, IHC-P, FC | IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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