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Recombinant Anti-human Maf Intrabody [(D-Arg)9] (CAT#: IAB-B020(A))

Recombinant anti-Maf intrabody linked to (D-Arg)9 works within cells and directs against the proto-oncoprotein Maf, expressed in E. coli cells.


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Normal Tissue
Figure 1 IHC staining of human duodenum
Figure 1 IHC staining of human duodenum
(Immunohistochemical staining of human duodenum shows moderate nuclear and cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/28289/59696_A_9_2_selected.jpg
Figure 2 Cerebral cortex
Figure 2 Cerebral cortex
(Glial cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Neuronal cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Neuropil Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10296/32682_B_9_5.jpg
Figure 3 Colon
Figure 3 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: nuclear Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10296/32682_A_8_3.jpg
Figure 4 Liver
Figure 4 Liver
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10296/32682_A_8_4.jpg
Figure 5 Kidney
Figure 5 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10296/32682_A_8_5.jpg
Figure 6 Testis
Figure 6 Testis
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10296/32682_A_5_6.jpg
Figure 7 Lymph node
Figure 7 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/10296/32682_A_9_8.jpg
RNA Expression
Figure 8 RNA cell line category: Group enriched (Karpas-707, RPMI-8226)
Figure 8 RNA cell line category: Group enriched (Karpas-707, RPMI-8226)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000178573-MAF

Specifications

  • Immunogen
  • human v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
  • Host Species
  • human
  • Type
  • scFv-(D-Arg)9
  • Cell Penetrating Peptide
  • (D-Arg)9
    It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.
  • Species Reactivity
  • human
  • Applications
  • Formats of immunological tests: Immunofluorescence; Enzyme-linked Immunosorbent Assay; Functional studies

Product Property

  • Purity
  • >95% as determined by analysis by SDS-PAGE
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Target

  • Alternative Names
  • MAF; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog; CCA4; c-MAF; CTRCT21; transcription factor Maf; c-maf proto-oncogene; proto-oncogene c-Maf; T lymphocyte c-maf long form; Avian musculoaponeurotic fibrosarcoma (MAF) protooncogene

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "MAF"

Recombinant Antibody

CAT Product Name Application Type
MOB-4079z Mouse Anti-MAF Recombinant Antibody (clone 35G11) WB, IP, IF, ELISA Mouse IgG1, κ
MOB-0267CT Recombinant Mouse anti-Human MAF Monoclonal antibody (EML558) WB
HPAB-693-FY Rabbit Anti-MAF Recombinant Antibody (HPAB-693-FY) WB, SPR Rabbit IgG

Intrabody

CAT Product Name Application Type
IAB-B020(G) Recombinant Anti-human Maf Intrabody [+36 GFP] FC, IF, FuncS scFv-(+36GFP)
IAB-B020(T) Recombinant Anti-human Maf Intrabody [Tat] CO-IP, FuncS scFv-Tat

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-2120 Hi-Affi™ Recombinant Rabbit Anti-MAF Monoclonal Antibody (DS2120AB) WB IgG

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-693-FY-S(P) Rabbit Anti-MAF Recombinant Antibody; scFv Fragment (HPAB-693-FY-S(P)) WB, ELISA Rabbit scFv

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-693-FY-F(E) Rabbit Anti-MAF Recombinant Antibody; Fab Fragment (HPAB-693-FY-F(E)) WB, ELISA Rabbit Fab

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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