Recombinant Mouse Anti-NGFR Antibody (ME20.4) (CAT#: NEUT-1778CQ)
This antibody is a mouse monoclonal antibody that binds specifically to NGF receptor, and it can neutralize the bioactivity of NGF receptor.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4765/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4765/if_selected.jpg
Figure 2 Adrenal gland
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4765/15396_B_6_5_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4765/15396_B_6_5_val_selected.jpg
Figure 3 Colon
(Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1995/5109_A_9_3.jpg
(Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1995/5109_A_9_3.jpg
Figure 4 Kidney
(Cells in glomeruli Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/143/2551_A_9_5.jpg
(Cells in glomeruli Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/143/2551_A_9_5.jpg
Figure 5 RNA cell line category: Group enriched (RH-30, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000064300-NGFR
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000064300-NGFR
Specifications
- Immunogen
- Human melanoma cell line, WM245.
- Host Species
- Mouse
- Type
- IgG1
- Specificity
- Recognizes NGF receptor
- Species Reactivity
- Human, Pig, Cat
- Clone
- ME20.4
- Applications
- Used for immunoassay techniques such as: Electron Microscopy; Enzyme-linked Immunosorbent Assay; Flow Cytometry; Immunocytochemistry/Immunofluorescence; Immunohistochemistry-Paraffin; Inhibition; Immunoprecipitation; Radioimmunoassay; Western Blot
- Conjugate
- Unconjugated
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze-thaw cycles.
Target
- Alternative Names
- NGFR; nerve growth factor receptor; CD271; p75NTR; TNFRSF16; p75(NTR); Gp80-LNGFR
- Gene ID
- 4804
- UniProt ID
- P08138
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "NGFR"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1958z | Mouse Anti-NGFR Recombinant Antibody (clone 32C5) | WB, FC, ICC, IHC | Mouse IgG1 |
| MOB-1877MZ | Recombinant Mouse Anti-Human NGFR Antibody (clone OHGS6) | FC, ICC/IF, IHC-P | Mouse antibody |
| MRO-1158-CN | Recombinant Rabbit Anti-NGFR Monoclonal Antibody (CBACN-421) | WB, IF, IHC, IP | Rabbit IgG |
| VS3-XY1166 | Mouse Anti-NGFR Recombinant Antibody (clone 2G2) | WB, IP, IF | Mouse IgG1 |
| VS3-FY1042 | Recombinant Mouse Anti-NGFR Antibody (clone 8G8H10) | ELISA, IHC, FC | Mouse IgG1 |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L038S | anti-Ngfr immunotoxin MC-192 (IgG)-Sap | Cytotoxicity assay, Functional assay |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1779CQ | Recombinant Mouse Anti-NGFR Antibody (5H1) | IHC, IP, Neut, WB | IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2440 | Hi-Affi™ Recombinant Rabbit Anti-NGFR Monoclonal Antibody (DS2440AB) | IHC-P | IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0276CQ-F(E) | Mouse Anti-NGFR Recombinant Antibody (clone MC192); Fab Fragment | ELISA, IHC, IP, WB | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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