Anti-Human NTRK2 Recombinant Antibody (C20) (CAT#: TAB-180CQ)

Recombinant monoclonal antibody to NTRK2. This product is a human antibody that can be potentially in the treatment of respiratory disorders such as rett syndrome.


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FuncS

Figure 1 is a graphical depiction of the drop in body weight and food intake seen in Mecp2 knockout mice to which TrkB agonist antibodies were administered.

Figure 1 is a graphical depiction of the drop in body weight and food intake seen in Mecp2 knockout mice to which TrkB agonist antibodies were administered.

FuncS

Figure 2 depiction of the improvement in grip strength and body fat composition in Mecp2 knockout mice to which TrkB agonist antibodies were administered.

Figure 2 depiction of the improvement in grip strength and body fat composition in Mecp2 knockout mice to which TrkB agonist antibodies were administered.

The square icons as data points represent the wild type (WT) mice treated with saline (SAL) or the TrkB agonist antibody C20; the circle icons as data points represent the knockout (KO) mice treated with saline (SAL) or the TrkB agonist antibody, C20.

FuncS

Figure 3 is a graphical depiction of the increased lifespan seen in Mecp2 knockout mice to which TrkB agonist antibodies were administered.

Figure 3 is a graphical depiction of the increased lifespan seen in Mecp2 knockout mice to which TrkB agonist antibodies were administered.

The knockout mice are described as KO and the wild type as WT. SAL means saline was administered, and C20 means TrkB agonist antibody was administered.

FuncS

Figure 4 is a graphical depiction of the increased lifespan seen in Mecp2 knockout mice to which TrkB agonist antibodies were administered.

Figure 4 is a graphical depiction of the increased lifespan seen in Mecp2 knockout mice to which TrkB agonist antibodies were administered.

The knockout mice are described as KO, and the TrkB agonist antibody is described as C20.


Specifications

  • Immunogen
  • Recombinant TrkB
  • Host Species
  • Human
  • Type
  • Human antibody
  • Specificity
  • Human
  • Species Reactivity
  • Human, Cynomolgous monkey, Mouse
  • Clone
  • C20
  • Applications
  • FuncS
  • Related Disease
  • Respiratory disorders

Applications

  • Application Notes
  • This antibody has been reported for use in Functional Assay.

Target

  • Alternative Names
  • NTRK2; Neurotrophic receptor tyrosine kinase 2; TRKB; trk-B; GP145-TrkB; BDNF/NT-3 growth factors receptor; tyrosine kinase receptor B; tropomyosin-related kinase B; BDNF-tropomyosine receptor kinase B

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone C20"

See other products for "NTRK2"

Human Antibody

CAT Product Name Application Type
TAB-180CQ-S(P) Anti-Human NTRK2 Recombinant Antibody scFv Fragment (C20) ELISA, FC, WB Human antibody
TAB-180CQ-F(E) Anti-Human NTRK2 Recombinant Antibody Fab Fragment (C20) ELISA, FC, WB Human antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-2509 Hi-Affi™ Recombinant Rabbit Anti-NTRK2 Monoclonal Antibody (DS2509AB) WB, IHC, IP IgG

Neuroscience Antibody

CAT Product Name Application Type
NS-095CN Human Anti-NTRK2 Recombinant Antibody (NS-095CN) ELISA Human IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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