Recombinant Mouse Anti-P. vivax AMA1 Antibody (F8.12.19) (CAT#: PABZ-148)

Recombinant Mouse Antibody (F8.12.19) is capable of binding to P. vivax AMA1, expressed in Chinese Hamster Ovary cells (CHO). The monoclonal antibody recognises a discontinuous epitope located on domain III of the ectoplasmic region, the major component being a loop containing a cystine knot.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Datasheet
  • MSDS
  • COA
IF

Figure 1 Pf3D7-AMA1 displays a type I TM topology at the plasma membrane of BHK-21 cells.

Figure 1 Pf3D7-AMA1 displays a type I TM topology at the plasma membrane of BHK-21 cells.

PfAMA1 transfected BHK-21 cells were subjected to IFA. Mouse MAb F8.12.19 recognizes extracellular PfAMA1 domain III that is accessible with or without permeabilization, whereas anti-Myc antibody labels the intracellular C-terminal Myc tag in permeabilized cells only.

Lamarque, M., Besteiro, S., Papoin, J., Roques, M., Vulliez-Le Normand, B., Morlon-Guyot, J., ... & Lebrun, M. (2011). The RON2-AMA1 interaction is a critical step in moving junction-dependent invasion by apicomplexan parasites. PLoS pathogens, 7(2), e1001276.


Specifications

  • Immunogen
  • P. vivax Apical membrane antigen 1
  • Host Species
  • Mouse
  • Derivation
  • Mouse
  • Type
  • IgG
  • Specificity
  • Tested positive against native P. vivax AMA1
  • Species Reactivity
  • P. vivax
  • Clone
  • F8.12.19
  • Applications
  • Can be useful in applications such as: Western Blot

Product Property

  • Purity
  • >95% by SDS-PAGE and HPLC analysis
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

Target

  • Alternative Names
  • AMA1; Apical membrane antigen 1

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone F8.12.19"

See other products for "AMA1"

Customer Reviews and Q&As

Submit a review or a question
There are currently no Customer reviews or questions for PABZ-148. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

© 2024 Creative Biolabs.
  • 0
  • 0
Cart

    Go to compare