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Anti-Human P2RX7 VHH Single Domain Antibody (1c81) (CAT#: TAB-0078CL-VHH)

This anitbody inhibits the biological activity of the P2X7 receptor, such as activation by ATP. It also blocks ATP-induced externaiization of PS and shedding of CD62L by human T cells.


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Normal Tissue
Figure 1 IHC staining of human cerebral cortex
Figure 1 IHC staining of human cerebral cortex
(Immunohistochemical staining of human cerebral cortex shows moderate positivity in neuropil.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34968/68670_B_8_5_selected.jpg
Figure 2 IHC staining of human cerebral cortex
Figure 2 IHC staining of human cerebral cortex
(Immunohistochemical staining of human cerebral cortex shows weak positivity in neuropil.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/42013/103582_B_7_5_selected.jpg
Figure 3 Cerebral cortex
Figure 3 Cerebral cortex
(Glial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34968/68670_B_7_5.jpg
Figure 4 Colon
Figure 4 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34968/68670_A_9_3.jpg
Figure 5 Kidney
Figure 5 Kidney
(Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34968/68670_A_9_5.jpg
Figure 6 Testis
Figure 6 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34968/68670_A_4_6.jpg
Figure 7 Skin
Figure 7 Skin
(Keratinocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Melanocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34968/68670_B_8_1.jpg
RNA Expression
Figure 8 RNA cell line category: Cell line enhanced (Karpas-707, RPMI-8226, SK-MEL-30, U-266/70, U-266/84)
Figure 8 RNA cell line category: Cell line enhanced (Karpas-707, RPMI-8226, SK-MEL-30, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000089041-P2RX7

Specifications

  • Host Species
  • Llama
  • Derivation
  • Phage display library
  • Type
  • Single domain antibody
  • Specificity
  • Human
  • Clone
  • 1c81
  • Applications
  • FC
  • Related Disease
  • P2X7 associated diseases

Target

  • Alternative Names
  • P2RX7; purinergic receptor P2X 7; P2X7

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "P2RX7"

Recombinant Antibody

CAT Product Name Application Type
MOB-2843z Mouse Anti-P2RX7 Recombinant Antibody (clone 24F9) WB, ELISA, FC, IHC Mouse IgG2b
HPAB-1590-FY Mouse Anti-P2RX7 Recombinant Antibody (HPAB-1590-FY) FC Mouse IgG2a
VS3-WK121 Mouse Anti-P2RX7 Recombinant Antibody (clone G1-D6) WB, ELISA Mouse IgG2b

Human Antibody

CAT Product Name Application Type
TAB-0916CL Human Anti-P2RX7 Recombinant Antibody (TAB-0916CL) WB, FC Human IgG
TAB-0916CL-S(P) Human Anti-P2RX7 Recombinant Antibody; scFv Fragment (TAB-0916CL-S(P)) WB, FC Human scFv
TAB-0916CL-F(E) Human Anti-P2RX7 Recombinant Antibody; Fab Fragment (TAB-0916CL-F(E)) WB, FC Human Fab

Single-domain Antibody

CAT Product Name Application Type
TAB-0079CL-VHH Llama Anti-P2RX7 Recombinant Antibody (TAB-0079CL-VHH) FC Llama VHH

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-2565 Hi-Affi™ Recombinant Rabbit Anti-P2RX7 Monoclonal Antibody (DS2565AB) WB, IP, FC, ICC/IF IgG

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-1590-FY-F(E) Mouse Anti-P2RX7 Recombinant Antibody; Fab Fragment (HPAB-1590-FY-F(E)) Inhib Mouse Fab

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-1590-FY-S(P) Mouse Anti-P2RX7 Recombinant Antibody; scFv Fragment (HPAB-1590-FY-S(P)) Inhib Mouse scFv

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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