This antibody can inhibit binding of PD-L1 to PD-1 and modulate immune responses mediated by TcR and CD28, in particular. It may be used in treating autoimmune diseases, inflammatory disorders, allergies, transplant rejection, cancer, and other immune system disorders.
Figure 1 Reactivity of IgG-converted antibodies with human or mouse PD-1 as determined by ELISA.
Figure 2 An ELISA demonstrating that selected PD-1 antibodies inhibit binding of PD-L1 to PD-1.
Figure 3 T-cell proliferation assays demonstrating that co-engagement by TcR and anti-PD-1 antibody PD1-17 or PD-L1.
Fc reduces proliferation. Co-engagement by TcR and anti-PD-1 J110 has no effect on proliferation.
Figure 4 Enhanced proliferation of primary T cells by PD1-17 in a soluble form.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-H55 | Human Anti-PDCD1 Recombinant Antibody (TAB-H55) | Inhib, Agonist | IgG4, κ |
TAB-0966CL | Human Anti-PDCD1 Recombinant Antibody (TAB-0966CL) | ELISA | Humanized antibody |
TAB-0975CL | Human Anti-PDCD1 Recombinant Antibody (TAB-0975CL) | ELISA | Humanized antibody |
TAB-0977CL | Anti-Human PDCD1 Recombinant Antibody (949gH1a) | FC | Humanized antibody |
TAB-0975CL-S(P) | Human Anti-PDCD1 Recombinant Antibody; scFv Fragment (TAB-0975CL-S(P)) | ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-295 | Human Anti-PDCD1 Recombinant Antibody (clone CBL27Q); Fab Fragment | WB, ELISA, FuncS | Human Fab |
HPAB-N0378-YC-F(E) | Human Anti-PDCD1 Recombinant Antibody (clone 273_C12_C05); Fab Fragment | FC, ELISA | Human Fab |
HPAB-N0379-YC-F(E) | Human Anti-PDCD1 Recombinant Antibody; Fab Fragment (HPAB-N0379-YC-F(E)) | FC, Block | Human Fab |
HPAB-N0380-YC-F(E) | Human Anti-PDCD1 Recombinant Antibody; Fab Fragment (HPAB-N0380-YC-F(E)) | ELISA, FuncS | Human Fab |
HPAB-0517LY-F(E) | Human Anti-PDCD1 Recombinant Antibody (clone MIL75); Fab Fragment | ELISA, Block | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0963CL | Mouse Anti-PDCD1 Recombinant Antibody (TAB-0963CL) | FC | Mouse IgG |
TAB-0964CL | Mouse Anti-PDCD1 Recombinant Antibody (TAB-0964CL) | ELISA, Inhib | Mouse IgG |
TAB-0965CL | Mouse Anti-PDCD1 Recombinant Antibody (TAB-0965CL) | ELISA | Mouse IgG |
TAB-0967CL | Anti-Human PDCD1 Recombinant Antibody (AB7) | ELISA, WB | |
TAB-0981CL-F(E) | Mouse Anti-PDCD1 Recombinant Antibody; Fab Fragment (TAB-0981CL-F(E)) | ELISA | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0974CL | Human Anti-PDCD1 Recombinant Antibody (TAB-0974CL) | ELISA | Chimeric (Mouse/Human) antibody |
TAB-0968CL-S(P) | Anti-Human PDCD1 Recombinant Antibody scFv Fragment (cAB7) | ELISA, WB | Chimeric antibody (mouse/human) |
TAB-0974CL-S(P) | Human Anti-PDCD1 Recombinant Antibody; scFv Fragment (TAB-0974CL-S(P)) | ELISA | Human scFv |
TAB-0968CL-F(E) | Anti-Human PDCD1 Recombinant Antibody Fab Fragment (cAB7) | ELISA, WB | Chimeric antibody (mouse/human) |
TAB-0974CL-F(E) | Human Anti-PDCD1 Recombinant Antibody; Fab Fragment (TAB-0974CL-F(E)) | ELISA | Chimeric (Mouse/Human) Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0961CL-S(P) | Anti-Human PDCD1 Recombinant Antibody scFv Fragment (PD1-17) | ELISA | Human antibody |
TAB-0962CL-S(P) | Anti-Mouse Pdcd1 Recombinant Antibody scFv Fragment (PD1-F2) | ELISA | Human antibody |
TAB-0970CL-S(P) | Human Anti-PDCD1 Recombinant Antibody; scFv Fragment (TAB-0970CL-S(P)) | ELISA | Human scFv |
TAB-0971CL-S(P) | Human Anti-PDCD1 Recombinant Antibody; scFv Fragment (TAB-0971CL-S(P)) | ELISA | Human scFv |
TAB-0972CL-S(P) | Human Anti-PDCD1 Recombinant Antibody; scFv Fragment (TAB-0972CL-S(P)) | ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1827CQ | Recombinant Rat Anti-Pdcd1 Antibody (29F.1A12) | BL, FC | IgG2a |
NEUT-1828CQ | Recombinant Hamster Anti-Pdcd1 Antibody (J43) | BL, WB | IgG |
NEUT-1829CQ | Recombinant Rat Anti-Pdcd1 Antibody (RMP1-14) | BL, WB | IgG2a |
NEUT-1830CQ | Recombinant Rat Anti-Pdcd1 Antibody (HA2-7B1) | BL | IgG2b |
NEUT-1831CQ | Recombinant Hamster Anti-Pdcd1 Antibody (MAB0839) | BL, FC | IgG2 |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1832CQ | Recombinant Mouse Anti-PDCD1 Antibody (CBL151) | Neut, WB | IgG2 |
NEUT-1834CQ | Recombinant Human Anti-PDCD1 Antibody (CBL1021) | Neut | IgG1, κ |
NEUT-1835CQ | Recombinant Mouse Anti-PDCD1 Antibody (9X21) | Neut, WB | IgG2 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-2622 | Hi-Affi™ Recombinant Rabbit Anti-PDCD1 Monoclonal Antibody (DS2622AB) | IHC | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0184-YC | Mouse Anti-PDCD1 Recombinant Antibody (HPAB-0184-YC) | FC, FuncS | Mouse IgG |
HPAB-0185-YC | Mouse Anti-PDCD1 Recombinant Antibody (HPAB-0185-YC) | FC, FuncS | Mouse IgG |
HPAB-0186-YC | Mouse Anti-PDCD1 Recombinant Antibody (HPAB-0186-YC) | ELISA, FC | Mouse IgG |
HPAB-0187-YC | Human Anti-PDCD1 Recombinant Antibody (HPAB-0187-YC) | ELISA, FC | Chimeric (mouse/human) IgG1, κ |
HPAB-0188-YC | Human Anti-PDCD1 Recombinant Antibody (HPAB-0188-YC) | ELISA, FC | Humanized IgG4 |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-900 | Afuco™ Anti-PDCD1 ADCC Recombinant Antibody (Pidilizumab), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
AFC-TAB-028ML | Afuco™ Anti-PDCD1 ADCC Recombinant Antibody (Gilvetmab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
AFC-TAB-012ML | Afuco™ Anti-PDCD1 ADCC Recombinant Antibody (Camrelizumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, BL | ADCC enhanced antibody |
AFC-TAB-770 | Afuco™ Anti-PDCD1 ADCC Recombinant Antibody (Nivolumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
AFC-TAB-H55 | Afuco™ Human Anti-PDCD1 Recombinant Antibody, ADCC Enhanced (AFC-TAB-H55) | FuncS, IF, Neut, ELISA, FC | IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-N0309-YC-VHH | Recombinant Humanized Anti-PDCD1 Single Domain Antibody (NOV011YC) | FC, ELISA | Humanized VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0731YY-S(P) | Human Anti-PDCD1 Recombinant Antibody; scFv Fragment (HPAB-0731YY-S(P)) | ELISA | Humanized scFv |
HPAB-0596YY-S(P) | Mouse Anti-PDCD1 Recombinant Antibody; scFv Fragment (HPAB-0596YY-S(P)) | ELISPOT, ICC, FuncS | Mouse scFv |
HPAB-0604YY-S(P) | Mouse Anti-PDCD1 Recombinant Antibody; scFv Fragment (HPAB-0604YY-S(P)) | ELISPOT, ICC, FuncS | Mouse scFv |
HPAB-0612YY-S(P) | Human Anti-PDCD1 Recombinant Antibody; scFv Fragment (HPAB-0612YY-S(P)) | FuncS | Humanized scFv |
HPAB-0589YY-S(P) | Mouse Anti-PDCD1 Recombinant Antibody; scFv Fragment (HPAB-0589YY-S(P)) | ELISA | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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