Recombinant Human Antibody (1E9-DB3) is capable of binding to Progesterone, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-Progesterone mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-Progesterone mAb and CL of human light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition.
Figure 1 pH-reactivity profiles of anti-17-OHP mAbs.
Radioimmunoassay using 3H-17-OHP was carried out at various pH as described in Materials and Methods. The percentage of the antibody-bound radioactivity to the total radioactivity added was plotted as a function of pH.
Jun-Ichi, S., Saeko, M., Tadao, T., Morihiro, N., & Yoshikazu, K. (1991). Molecular characterization of monoclonal anti-steroid antibodies: primary structures of the variable regions of seven antibodies specific for 17α-hydroxyprogesterone or 11-deoxycortisol and their pH-reactivity profiles. Molecular immunology, 28(10), 1063-1072.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
PSBL-311 | Human Anti-P4 Recombinant Antibody (clone 1E9-DB3); scFv Fragment | WB, ELISA, FuncS | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-311 | Human Anti-P4 Recombinant Antibody (clone 1E9-DB3); Fab Fragment | WB, ELISA, FuncS | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-159 | Recombinant Mouse Anti-Progesterone Antibody (DB3) | Neut, FuncS | IgG |
PABX-159-S (P) | Recombinant Mouse Anti-Progesterone Antibody scFv Fragment (DB3) | Neut, FuncS | scFv |
PABX-159-F (E) | Recombinant Mouse Anti-Progesterone Antibody Fab Fragment (DB3) | Neut, FuncS | Fab |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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