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Anti-RAS Intrabody [+36GFP] (IAB-B009(G))

Recombinant anti-RAS intrabody in fusion with +36GFP works within cells to bind human RAS, expressed in E. coli cells. An intracellular antibody constructed by the single chain antibody can inhibit proliferations and invasion abilities of the human tumor cells with highly expressed p21ras proteins.      

Specifications
Immunogen
human Kirsten rat sarcoma viral oncogene homolog
Host
human
Type
scFv-(+36GFP)
Cell Penetrating Peptide
+36 GFP
GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
Species Reactivity
human
Applications
Formats of immunological tests: Immunofluorescence; Enzyme-linked Immunosorbent Assay; Functional studies
Target
Alternative Names
KRAS; Kirsten rat sarcoma viral oncogene homolog; NS; NS3; CFC2; KRAS1; KRAS2; RASK2
Entrez Gene ID
3845
UniProt ID
A0A024RAV5

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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