Products

Anti-RELA Intrabody [+36GFP] (IAB-B027(G))

Recombinant anti-RELA intrabody in fusion with +36GFP works within cells against RELA, expressed in E. coli cells. This intrabody against p65 subunit can prevent nuclear factor nB (NF-nB) transcriptional activity in glioma cells andbindinhibit the expression of its target genes involved in the invasion and angiogenesis of human gliomas.      

Specifications
Immunogen
human v-rel avian reticuloendotheliosis viral oncogene homolog A
Host
human
Type
scFv-(+36GFP)
Cell Penetrating Peptide
+36 GFP
GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
Species Reactivity
human
Applications
Products can be used for: Immunofluorescence; Enzyme-linked Immunosorbent Assay; Functional studies
Target
Alternative Names
RELA; v-rel avian reticuloendotheliosis viral oncogene homolog A; p65; NFKB3; transcription factor p65; NF-kappa-B p65delta3; nuclear factor NF-kappa-B p65 subunit; v-rel reticuloendotheliosis viral oncogene homolog A
Entrez Gene ID
5970
UniProt ID
Q04206

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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