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Anti-RTN4 Therapeutic Antibody (TAB-541CL)

Recombinant Mouse monoclonal antibody expressed in CHO binding to Human RTN4. TAB-541CL is an anti-nogo-A monoclonal antibody used for treatment of amyotrophic lateral sclerosis. Study show that treatment with anti-Nogo-A antibody improves neuromuscular function in the SOD1(G93A) mouse model of ALS, at least during the earlier stages of disease and suggest that pharmacological inhibition of Nogo-A may be a disease-modifying approach in ALS.      

Specifications
Host
Mouse
Derivation
Mouse
Type
Antibody
Species Reactivity
Human
Related Disease
Amyotrophic lateral sclerosis
Target
Alternative Names
RTN4; reticulon 4; ASY; NSP; NOGO; NOGOC; RTN-X; NOGO-A
Entrez Gene ID
57142
UniProt ID
Q9NQC3

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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