Recombinant Mouse Anti-Ricin Antibody (RAC18) (CAT#: PABX-165)
Anti-Ricin antibody is a Mouse antibody of IgG κ class that binds to an Ricin. This antibody is a neutralizing antibody.
Specific Inquiry
FuncS
Figure 1 Protective effects of Ab-DeliverlN (DellN)-mediated intracellular delivery of monoclonal RAC18 anti-ricin A-chain monoclonal antibody (RAC18 mAb) against ricin-induced cytotoxicity.
RAW264.7 cells were incubated with naked antibodies or DellN-encapsulated antibodies for 8 h. After 3 washes with PBS to remove extracellular antibodies, ricin (100 ng/mL) was added and incubated for additional 24 h. Cell viability was quantitated using the MTT assay. As controls for the neutralizing effects of anti-ricin antibodies, ricin was co-incubated with naked dgA Ab, RAC18 mAb or control IgG.
Wu, F., Fan, S., Martiniuk, F., Pincus, S., Müller, S., Kohler, H., & Tchou-Wong, K. M. (2010). Protective effects of anti-ricin A-chain antibodies delivered intracellularly against ricin-induced cytotoxicity. World journal of biological chemistry, 1(5), 188.
IF
Figure 2 Intracellular localization of fluorescent-labeled ricin and fluorescent-labeled DelIN-encapsulated RAC18 mAb by immunofluorescent staining.
Immunofluorescent staining of RAW264.7 cells treated with Alexa 488-labeled ricin and DelIN-Alexa 594-labeled RAC18 mAb (red).
Wu, F., Fan, S., Martiniuk, F., Pincus, S., Müller, S., Kohler, H., & Tchou-Wong, K. M. (2010). Protective effects of anti-ricin A-chain antibodies delivered intracellularly against ricin-induced cytotoxicity. World journal of biological chemistry, 1(5), 188.
Specifications
- Immunogen
- Purified RAC
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- IgG
- Specificity
- Tested positive against native Ricinus communis Ricin
- Species Reactivity
- Ricinus communis
- Clone
- RAC18
- Applications
- FuncS, IF
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- This antibody has been reported for use in Functional Assay and Immunofluorescence. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. should be carefully titrated in specific assays.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone RAC18"
See other products for "Ricin"
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-318 | Recombinant Mouse Anti-Ricin Antibody Fab Fragment (6C2) | Neut, FuncS | Fab |
| PFBL-685 | Mouse Anti-Ricin Recombinant Antibody (clone mAb RAC18); Fab Fragment | Neut | Mouse Fab |
| HPAB-1607-FY-S(P) | Human Anti-Ricin Recombinant Antibody (clone REV8); Fab Fragment | WB, ELISA, IP | Chimeric (macaque/human) Fab |
| PFBS-0050 | Mouse Anti-Ricin Recombinant Antibody; Fab Fragment (PFBS-0050) | ELISA, Neut, FuncS | Mouse Fab |
| PFBS-0068 | Human Anti-Ricin Recombinant Antibody; Fab Fragment (PFBS-0068) | ELISA, Neut, FuncS | Humanized Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-685 | Mouse Anti-Ricin Recombinant Antibody (clone mAb RAC18); scFv Fragment | Neut | Mouse scFv |
| FAMAB-0060JF-S(P) | Monkey Anti-Ricin Recombinant Antibody (clone 43RCA); scFv Fragment | WB, ELISA, FuncS | Monkey scFv |
| FAMAB-0310JF-S(P) | Mouse Anti-Ricin Recombinant Antibody (clone 3E1); scFv Fragment | WB, ELISA, FuncS | Mouse scFv |
| PSBS-0050 | Mouse Anti-Ricin Recombinant Antibody; scFv Fragment (PSBS-0050) | ELISA, Neut, FuncS | Mouse scFv |
| PSBS-0068 | Human Anti-Ricin Recombinant Antibody; scFv Fragment (PSBS-0068) | ELISA, Neut, FuncS | Humanized scFv |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-165-S (P) | Recombinant Mouse Anti-Ricin Antibody scFv Fragment (RAC18) | Neut, FuncS | scFv |
| PABX-165-F (E) | Recombinant Mouse Anti-Ricin Antibody Fab Fragment (RAC18) | Neut, FuncS | Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1607-FY | Human Anti-Ricin Recombinant Antibody (clone REV8) | WB, ELISA, IP | Chimeric (macaque/human) IgG |
| HPAB-1608-FY | Human Anti-Ricin Recombinant Antibody (clone REV7) | WB, ELISA, IP | Chimeric (macaque/human) IgG |
| FAMAB-0060JF | Monkey Anti-Ricin Recombinant Antibody (clone 43RCA) | WB, ELISA, IHC, Neut | Monkey IgG |
| PABS-0050 | Mouse Anti-Ricin Recombinant Antibody (PABS-0050) | ELISA, Neut, FuncS | Mouse IgG |
| PABS-0068 | Human Anti-Ricin Recombinant Antibody (PABS-0068) | ELISA, Neut, FuncS | Humanized IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for PABX-165. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.