Anti-SARS-CoV S Recombinant Antibody (S-9-11) (CAT#: MRO-655LC)

This product is a recombinant mouse anti-SARS-CoV monoclonal antibody clone S-9-11. S-9-11 specifically binds to spike protein associated with SARS-CoV and can be potentially used in the diagnosis and treatment studies of SARS-CoV infection.


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Neut

Figure 1 Neutralizing activity of mAb S911 at different doses was determined by syncytia inhibition assay.

Figure 1 Neutralizing activity of mAb S911 at different doses was determined by syncytia inhibition assay.

Immunized mouse sera collected 1 week after the second booster immunization was screened by syncytia inhibition assay. 'No ACE2': HEK293T cells without ACE2 plasmid transfection. '+': positive control in which HEK293T cells were transfected with ACE2 plasmid and no antiserum added. Neutralizing effects of normal mouse sera (N) and immunized mouse sera were measured in groups of ACE2 transfected HEK293T cells.

Bian, C., Zhang, X., Cai, X., Zhang, L., Chen, Z., Zha, Y., ... & Yuan, J. (2009). Conserved amino acids W423 and N424 in receptorbinding domain of SARSCoV are potential targets for therapeutic monoclonal antibody. Virology, 383(1), 3946.


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse antibody
  • Specificity
  • Severe acute respiratory syndrome coronavirus
  • Clone
  • S-9-11
  • Applications
  • Neut
  • Related Disease
  • SARS-CoV infection

Applications

  • Application Notes
  • This antibody has been reported for use in Neutralization.

Target

  • Alternative Names
  • SARS coronavirus; SARS-CoV; SARS coronavirus spike protein; SARS-CoV S; E2 glycoprotein precursor; E2

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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Epitope-Specific Antibody

CAT Product Name Application Type
EPAF-1139CQ Recombinant Human Anti-SARS-CoV S Antibody (m396) ELISA IgG1

Recombinant Antibody

Single-domain Antibody

CAT Product Name Application Type
NAB-474CQ Camelid Anti-SARS-CoV S Recombinant Single Domain Antibody (NAB-474CQ) Neut Camelid VHH

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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