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  • Anti-Human SEMA3A Recombinant Antibody, Humanized

Anti-Human SEMA3A Recombinant Antibody, Humanized (CAT#: TAB-556CL)

Recombinant Humanized monoclonal antibody expressed in CHO binding to Human SEMA3A. The anti-Sema3A antibody enables effective prevention and treatment of a disease, in which Sema3A protein participates, such as a neurodegenerative disease, autoimmune disease, inflammatory disease, cancer, infectious disease, etc. or disseminated intravascular coagulation syndrome.


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  • Datasheet
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Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52235/if_selected.jpg
Figure 2 IHC staining of human liver
Figure 2 IHC staining of human liver
(Immunohistochemical staining of human liver shows cytoplasmic positivity in hepatocytes.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29447/ihc_selected.jpg
Figure 3 IF staining of human cell line A-431
Figure 3 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52235/816_B11_3_blue_red_green.jpg
Figure 4 IF staining of human cell line U-251 MG
Figure 4 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/52235/790_B11_1_blue_red_green.jpg
Normal Tissue
Figure 5 Cerebral cortex
Figure 5 Cerebral cortex
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Neuronal cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29447/61370_B_7_5.jpg
Figure 6 Colon
Figure 6 Colon
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29447/61370_A_8_3.jpg
Figure 7 Liver
Figure 7 Liver
(Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29447/61370_A_7_4.jpg
Figure 8 Kidney
Figure 8 Kidney
(Cells in glomeruli
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29447/61370_A_7_5.jpg
Figure 9 Testis
Figure 9 Testis
(Cells in seminiferous ducts
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29447/61370_A_4_6.jpg
Figure 10 Lymph node
Figure 10 Lymph node
(Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29447/61370_A_9_8.jpg
RNA Expression
Figure 11 RNA cell line category: Cell line enhanced (AF22, BJ, fHDF/TERT166)
Figure 11 RNA cell line category: Cell line enhanced (AF22, BJ, fHDF/TERT166)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000075213-SEMA3A

Specifications

  • Derivation
  • Humanized
  • Type
  • Antibody
  • Species Reactivity
  • Human
  • Related Disease
  • Neurodegenerative Disease; Autoimmune Disease; Inflammatory Disease; Cancer; Infectious Disease

Product Property

  • Purity
  • >90% assessed by SDS-PAGE
  • Storage
  • ≥1 year at -20°C. If the reconstituted antibody cannot be used within two weeks, it should be aliquoted into smaller vials and stored at -20°C

Target

  • Alternative Names
  • SEMA3A; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A; HH16; SemD; COLL1; SEMA1; SEMAD; SEMAL; coll-1; Hsema-I; SEMAIII; Hsema-III; semaphorin-3A; collapsin 1; semaphorin D; semaphorin L; semaphorin III

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "SEMA3A"

Single-domain Antibody

CAT Product Name Application Type
NAB-2258-VHH Recombinant Anti-Human SEMA3A VHH Single Domain Antibody IHC, ICC, IP, ChiP, Neut Llama VHH

Recombinant Antibody

CAT Product Name Application Type
MOB-2222z Mouse Anti-SEMA3A Recombinant Antibody (clone 28B6) WB, ICC, IHC, IP Mouse IgG1, κ
MOB-1860CT Recombinant Mouse anti-Human SEMA3A Monoclonal antibody (EML1051) WB
HPAB-3172LY Human Anti-SEMA3A Recombinant Antibody (HPAB-3172LY) Neut, Inhib Human IgG
HPAB-3173LY Human Anti-SEMA3A Recombinant Antibody (HPAB-3173LY) Neut, Inhib Human IgG
HPAB-3174LY Human Anti-SEMA3A Recombinant Antibody (HPAB-3174LY) FuncS, Neut, Inhib Human IgG

Humanized Antibody

CAT Product Name Application Type
TAB-421CT Humanized Anti-SEMA3A Recombinant Antibody (TAB-421CT) WB, ELISA Humanized IgG
TAB-421CT-S(P) Humanized Anti-SEMA3A Recombinant Antibody; scFv Fragment (TAB-421CT-S(P)) WB, ELISA Humanized scFv
TAB-421CT-F(E) Humanized Anti-SEMA3A Recombinant Antibody; Fab Fragment (TAB-421CT-F(E)) WB, ELISA Humanized Fab

Neuroscience Antibody

CAT Product Name Application Type
NS-078CN Human Anti-SEMA3A Recombinant Antibody (NS-078CN) ELISA Chimeric (avian/human) IgG1
NS-079CN Human Anti-SEMA3A Recombinant Antibody (NS-079CN) ELISA Chimeric (avian/human) IgG1
NS-078CN-F(E) Human Anti-SEMA3A Recombinant Antibody; Fab Fragment (NS-078CN-F(E)) ELISA Chimeric (avian/human) Fab
NS-079CN-F(E) Human Anti-SEMA3A Recombinant Antibody; Fab Fragment (NS-079CN-F(E)) ELISA Chimeric (avian/human) Fab
NS-078CN-S(P) Human Anti-SEMA3A Recombinant Antibody; scFv Fragment (NS-078CN-S(P)) ELISA Human scFv

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-3172LY-S(P) Human Anti-SEMA3A Recombinant Antibody; scFv Fragment (HPAB-3172LY-S(P)) ELISA, Inhib Human scfv
HPAB-3173LY-S(P) Human Anti-SEMA3A Recombinant Antibody; scFv Fragment (HPAB-3173LY-S(P)) ELISA, Inhib Human scfv
HPAB-3174LY-S(P) Human Anti-SEMA3A Recombinant Antibody; scFv Fragment (HPAB-3174LY-S(P)) ELISA, Inhib Human scfv

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-3172LY-F(E) Human Anti-SEMA3A Recombinant Antibody; Fab Fragment (HPAB-3172LY-F(E)) ELISA, Inhib Human Fab
HPAB-3173LY-F(E) Human Anti-SEMA3A Recombinant Antibody; Fab Fragment (HPAB-3173LY-F(E)) ELISA, Inhib Human Fab
HPAB-3174LY-F(E) Human Anti-SEMA3A Recombinant Antibody; Fab Fragment (HPAB-3174LY-F(E)) ELISA, Inhib Human Fab

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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