CT140 is a humanized version of murine monoclonal antibody 33B8 variable heavy chain fused to an IgG4 Fc construct. The binding of CT140 to rat, mouse, rabbit and human PAI-1 was determined by P-ELISA. CT140 specifically bound human and rabbit PAI-1 to a greater extent than murine and rat PAI-1. This humanized anti-PAI-1 antibody (CT140) can bind and neutralize PAI-1 by converting PAI-1 to its latent form or increasing proteolytic cleavage. It is shown to protect mice from liver fibrosis, indicating that it decreases the population of myofibroblasts, the most prominent population of matrix producing cells.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
DrMAB-1148 | Recombinant Human Anti-Human SERPINE1 Antibody scFv Fragment, clone 1040-1F6 | ELISA, WB, ICH, IP | scFv |
DrMAB-1151 | Recombinant Human Anti-Human SERPINE1 Antibody scFv Fragment, clone 1040-1F6 [HRP] | ELISA, WB, ICH, IP | scFv |
HPAB-0269-FY-S(P) | Human Anti-SERPINE1 Recombinant Antibody (clone PICK167-A01-fgl); scFv Fragment | FuncS, Inhib | Human scFv |
HPAB-AP787-YC-S(P) | Human Anti-SERPINE1 Recombinant Antibody (clone CT240); scFv Fragment | ELISA, Neut | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0924CL | Mouse Anti-SERPINE1 Recombinant Antibody (TAB-0924CL) | ELISA | Mouse IgG1 |
TAB-0924CL-S(P) | Mouse Anti-SERPINE1 Recombinant Antibody; scFv Fragment (TAB-0924CL-S(P)) | ELISA | Mouse scFv |
TAB-0924CL-F(E) | Mouse Anti-SERPINE1 Recombinant Antibody; Fab Fragment (TAB-0924CL-F(E)) | ELISA | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0925CL | Human Anti-SERPINE1 Recombinant Antibody (TAB-0925CL) | ELISA | Humanized IgG |
TAB-0925CL-F(E) | Human Anti-SERPINE1 Recombinant Antibody; Fab Fragment (TAB-0925CL-F(E)) | ELISA | Humanized Fab |
TAB-0926CL-F(E) | Anti-Human SERPINE1 Recombinant Antibody Fab Fragment (CT110) | Immunohistochemical staining, WB, ELISA | Humanized antibody |
TAB-0927CL-F(E) | Anti-Human SERPINE1 Recombinant Antibody Fab Fragment (CT140) | Immunohistochemical staining, WB, ELISA | Humanized antibody |
TAB-0928CL-F(E) | Anti-Human SERPINE1 Recombinant Antibody Fab Fragment (55F4C12) | Immunohistochemical staining, WB, ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0929CL | Human Anti-SERPINE1 Recombinant Antibody (TAB-0929CL) | ELISA | Human antibody |
TAB-0923CL-S(P) | Human Anti-SERPINE1 Recombinant Antibody; scFv Fragment (TAB-0923CL-S(P)) | ELISA | Human scFv |
TAB-0929CL-S(P) | Human Anti-SERPINE1 Recombinant Antibody; scFv Fragment (TAB-0929CL-S(P)) | ELISA | Human scFv |
TAB-0923CL-F(E) | Human Anti-SERPINE1 Recombinant Antibody; Fab Fragment (TAB-0923CL-F(E)) | ELISA | Human Fab |
TAB-0929CL-F(E) | Human Anti-SERPINE1 Recombinant Antibody; Fab Fragment (TAB-0929CL-F(E)) | ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1525CT | Recombinant Mouse anti-Human SERPINE1 Monoclonal antibody (4B230) | WB | |
HPAB-0269-FY | Human Anti-SERPINE1 Recombinant Antibody (clone PICK167-A01-fgl) | FuncS, Inhib | Human IgG1, κ |
HPAB-AP787-YC | Human Anti-SERPINE1 Recombinant Antibody (clone CT240) | ELISA, Neut | Humanized IgG, κ |
VS3-WK183 | Mouse Anti-SERPINE1 Recombinant Antibody (clone H9-D5) | WB, ELISA | Mouse IgG1 |
VS3-FY1328 | Recombinant Rabbit Anti-SERPINE1 Antibody (clone R05-6J6) | WB, ICC, IF, IP | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1944CQ | Recombinant Mouse Anti-SERPINE1 Antibody (124K1) | ELISA, Neut, WB | IgG1, κ |
NEUT-1945CQ | Recombinant Mouse Anti-SERPINE1 Antibody (12V3) | Neut, WB | IgG1 |
NEUT-1946CQ | Recombinant Mouse Anti-SERPINE1 Antibody (33B8) | ELISA, Neut, WB | IgG1, κ |
NEUT-1947CQ | Recombinant Mouse Anti-SERPINE1 Antibody (33H1F7) | ELISA, IHC-P, Neut, WB | IgG1 |
NEUT-1948CQ | Recombinant Mouse Anti-SERPINE1 Antibody (CBL946) | ELISA, IHC, Neut, WB | IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-3223 | Hi-Affi™ Recombinant Rabbit Anti-SERPINE1 Monoclonal Antibody (DS3223AB) | WB, IP | IgG |
MOR-4719 | Hi-Affi™ Recombinant Rabbit Anti-SERPINE1 Monoclonal Antibody (TH233DS) | WB | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0269-FY-F(E) | Human Anti-SERPINE1 Recombinant Antibody (clone PICK167-A01-fgl); Fab Fragment | FuncS, Inhib | Human Fab, κ |
HPAB-AP787-YC-F(E) | Human Anti-SERPINE1 Recombinant Antibody (clone CT240); Fab Fragment | ELISA, Neut | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PABJ-0054 | Camelid Anti-SERPINE1 Recombinant Antibody (clone 2g-42/Nb42) | ELISA, Inhib | Camelid VHH |
PABJ-0055 | Camelid Anti-SERPINE1 Recombinant Antibody (clone 2w-64/Nb64) | ELISA, Inhib | Camelid VHH |
There are currently no Customer reviews or questions for TAB-0927CL. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.