cKM4018 is a chimeric antibody against ASCT2. The anti-ASCT2 antibody cKM4018 specifically binds system asc amino acid transporter 2, and can be used for treating the disease and disorders disease relating to system ASC amino acid transporter 2, such as cancer.
Figure 1 The reactivity of an anti-ASCT2 human chimeric antibody to human ASCT2-myc/His gene-introduced CHO cells (ASCT2/CHO) and human multiple myeloma cell line OPM-2 by means of fluorescent cell staining (flow cytometer).
The abscissa represents an antibody concentration ( μg/ml), and the ordinate represents a mean fluorescence intensity. The mean fluorescence intensity is indicated by ◯ and solid line for cKM4008, by ∆ and solid line for cKM4012, and by ■ and solid line for cKM4018.
Figure 2 The ADCC activity of an anti-ASCT2 human chimeric antibody on the human multiple myeloma cell line KMS-11.
The abscissa represents an antibody concentration ( ng/ml), and the ordinate represents an ADCC activity. The ADCC activity is indicated by ◯ and solid line for cKM4008, by ∆ and solid line for cKM4012, and by ■ and solid line for cKM4018.
Figure 3 The CDC activity of an anti-ASCT2 human chimeric antibody on human ASCT2-myc/His gene-introduced CHO cells (ASCT2/CHO) and human colorectal cancer cell line Colo205.
The abscissa represents an antibody concentration ( μg/ml), and the ordinate represents a CDC activity. The CDC activity is indicated by ◯ and solid line for cKM4008, by ∆ and solid line for cKM4012, and by ■ and solid line for cKM4018.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-1002CLV | Anti-Human SLC1A5 Recombinant Antibody (KM3842) | ELISA | |
TAB-1003CLV | Anti-Human SLC1A5 Recombinant Antibody (KM3998) | FC, Inhib | |
TAB-1004CLV | Anti-Human SLC1A5 Recombinant Antibody (KM4000) | FC, Inhib | |
TAB-1005CLV | Anti-Human SLC1A5 Recombinant Antibody (KM4001) | FC, Inhib | |
TAB-1006CLV | Anti-Human SLC1A5 Recombinant Antibody (KM4008) | FC, Inhib |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-1009CLV | Anti-Human SLC1A5 Recombinant Antibody (cKM4008) | FC, ADCC, CDC, Inhib | Chimeric antibody (mouse/human) |
TAB-1010CLV | Anti-Human SLC1A5 Recombinant Antibody (cKM4012) | FC, ADCC, CDC | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-N0245-YC | Human Anti-SLC1A5 Recombinant Antibody (HPAB-N0245-YC) | Cyt, FC, FuncS | Humanized IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-N0245-YC-S(P) | Human Anti-SLC1A5 Recombinant Antibody; scFv Fragment (HPAB-N0245-YC-S(P)) | Cyt, FC, FuncS | Humanized scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-N0245-YC-F(E) | Human Anti-SLC1A5 Recombinant Antibody; Fab Fragment (HPAB-N0245-YC-F(E)) | Cyt, FC, FuncS | Humanized Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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