Products

Anti-SMAD7 Intrabody [+36GFP] (IAB-B025(G))

Recombinant anti-SMAD7 intrabody in fusion with +36GFP works within cells to bind SMAD7, expressed in CHO cells. The intrabody relates to inhibito Smad7 expression or function for the preparation of a pharmaceutical composition for the prevention, amelioration or treatment of a disease of the central nervous system and/or diseases related and/or caused by said disease of the central nervous system.      

Specifications
Immunogen
human SMAD family member 7
Host
llama
Type
vhh-(+36GFP)
Cell Penetrating Peptide
+36 GFP
GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
Species Reactivity
human
Applications
Antibody assay: Enzyme-linked Immunosorbent Assay; Immunocytochemistry; Functional studies
Target
Alternative Names
SMAD7; SMAD family member 7; CRCS3; MADH7; MADH8; mothers against decapentaplegic homolog 7; hSMAD7; MAD homolog 8
Entrez Gene ID
4092
UniProt ID
O15105

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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