Recombinant anti-SNCA intrabody in fusion with +36GFP works within cells to bind human monomeric wild-type SNCA, expressed in E. coli cells. The intrabody stabilizes detergent-soluble monomeric syn and inhibits the formation of detergent-insoluble high-molecular-weight syn species. In addition, the intrabody ameliorates the decreased cell adhesion that characterizes the syn-overexpressing cells. Anti-SNCA intrabodies may represent novel molecular therapeutics for synucleinopathies, with implications for other neurodegenerative disorders caused by misfolded accumulated proteins.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1365z | Mouse Anti-SNCA Recombinant Antibody (clone 8F8) | ELISA, FC, ICC, IF, WB | Mouse IgG1 |
HPAB-N0389-YC | Human Anti-SNCA Recombinant Antibody (HPAB-N0389-YC) | ELISA, IP, FuncS | Human IgG |
HPAB-N0390-YC | Mouse Anti-SNCA Recombinant Antibody (HPAB-N0390-YC) | ELISA, IP, FuncS | Mouse IgG |
MRO-0071-CN | Recombinant Rabbit Anti-SNCA Monoclonal Antibody (JB42-33) | WB, IF, IHC, IP, FC | Rabbit IgG |
ZG-126R | Mouse Anti-SNCA Recombinant Antibody (ZG-126R) | WB, ELISA, IHC | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
IAB-B031(A) | Recombinant Anti-human SNCA Intrabody [(D-Arg)9] | FC, IF, FuncS | scFv-(D-Arg)9 |
IAB-B031(T) | Recombinant Anti-human SNCA Intrabody [Tat] | ELISA, IF, Neut, FuncS | scFv-Tat |
CAT | Product Name | Application | Type |
---|---|---|---|
PNBL-086 | Recombinant Anti-SNCA VHH Single Domain Antibody (NbSyn2) | WB, FuncS | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0740CLV | Rabbit Anti-SNCA Recombinant Antibody (TAB-0740CLV) | ELISA | Chimeric antibody (mouse/rabbit) |
TAB-0740CLV-F(E) | Rabbit Anti-SNCA Recombinant Antibody; Fab Fragment (TAB-0740CLV-F(E)) | ELISA | Chimeric antibody (mouse/rabbit) |
TAB-0740CLV-S(P) | Rabbit Anti-SNCA Recombinant Antibody; scFv Fragment (TAB-0740CLV-S(P)) | ELISA | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0741CLV-F(E) | Mouse Anti-SNCA Recombinant Antibody; Fab Fragment (TAB-0741CLV-F(E)) | ELISA | Mouse Fab |
TAB-0742CLV-F(E) | Mouse Anti-SNCA Recombinant Antibody; Fab Fragment (TAB-0742CLV-F(E)) | ELISA | Mouse Fab |
TAB-0743CLV-F(E) | Mouse Anti-SNCA Recombinant Antibody; Fab Fragment (TAB-0743CLV-F(E)) | ELISA | Mouse Fab |
TAB-0744CLV-F(E) | Mouse Anti-SNCA Recombinant Antibody; Fab Fragment (TAB-0744CLV-F(E)) | ELISA | Mouse Fab |
TAB-0745CLV-F(E) | Mouse Anti-SNCA Recombinant Antibody; Fab Fragment (TAB-0745CLV-F(E)) | ELISA | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1977CQ | Recombinant Human Anti-SNCA Antibody (NAC32) | IHC, WB, BL | IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-0154 | Hi-Affi™ Recombinant Rabbit Anti-alpha + beta Synuclein Monoclonal Antibody (DS154AB) | FC, WB, ICC/IF | IgG |
MOR-3354 | Hi-Affi™ Recombinant Rabbit Anti-SNCA Monoclonal Antibody (DS3354AB) | IHC, ICC, FC, IP | IgG |
MOR-4530 | Hi-Affi™ Recombinant Rabbit Anti-SNCA Monoclonal Antibody (TH38DS) | WB, IF, ICC, IHC-P, FC | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
NS-005CN | Mouse Anti-SNCA Recombinant Antibody (NS-005CN) | WB, ELISA, FC | Mouse IgG2a |
NS-088CN | Mouse Anti-SNCA Recombinant Antibody (NS-088CN) | WB, ELISA, IHC | Mouse IgG2a |
CAT | Product Name | Application | Type |
---|---|---|---|
NS-005CN-F(E) | Mouse Anti-SNCA Recombinant Antibody; Fab Fragment (NS-005CN-F(E)) | WB, ELISA, FC | Mouse Fab |
NS-088CN-F(E) | Mouse Anti-SNCA Recombinant Antibody; Fab Fragment (NS-088CN-F(E)) | WB, ELISA, IHC | Mouse Fab |
FAMAB-0260-CN-F(E) | Human Anti-SNCA Recombinant Antibody (clone D10); Fab Fragment | ELISA | Human Fab |
FAMAB-0261-CN-F(E) | Human Anti-SNCA Recombinant Antibody (clone 6E); Fab Fragment | ELISA | Human Fab |
HPAB-N0389-YC-F(E) | Human Anti-SNCA Recombinant Antibody; Fab Fragment (HPAB-N0389-YC-F(E)) | ELISA, IP, FuncS | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-N0389-YC-S(P) | Human Anti-SNCA Recombinant Antibody; scFv Fragment (HPAB-N0389-YC-S(P)) | ELISA, IP, FuncS | Human scFv |
HPAB-N0390-YC-S(P) | Mouse Anti-SNCA Recombinant Antibody; scFv Fragment (HPAB-N0390-YC-S(P)) | ELISA, IP, FuncS | Mouse scFv |
HPAB-653-FY-S(P) | Mouse Anti-SNCA Recombinant Antibody; scFv Fragment (HPAB-653-FY-S(P)) | WB, IP, ELISA | Mouse scFv |
HPAB-654-FY-S(P) | Mouse Anti-SNCA Recombinant Antibody; scFv Fragment (HPAB-654-FY-S(P)) | ELISA | Mouse scFv |
HPAB-0753-WJ-S(P) | Human Anti-SNCA Recombinant Antibody; scFv Fragment (HPAB-0753-WJ-S(P)) | ELISA | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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