Recombinant Mouse Antibody (3E2) is capable of binding to Staphylococcal enterotoxin B (SEB) , expressed in Chinese Hamster Ovary cells (CHO). This is a neutralizing mAb that recognizes SEB with high specificity and sub-nanomolar affinity. It strongly inhibits SEB-induced T cell proliferation and activation.
Figure 1 Fluorescence photomicrographs showing the effects of various fusion proteins and monoclonal antibody controls.
(A) Representative image of C. parvum sporozoites after a 30-min exposure to either PBS, the CHO cell supernatant, 4H9-G1, 4H9-G2b, the 18.44 MAb, 4H9-G1- PLA2, 3E2-G1, or the 3E2 MAb. (B) Representative image of C. parvum sporozoites after a 30-min exposure to either 4H9-G2b-LL37, 4H9-G1- LL37, 3E2-G1-LL37, 3E2-Mhalf-LL37, or 3E2-Mmono-LL37. (C) C. parvum sporozoites after exposure to 18.44-G1-PLA2 for 30 min. (D) Heatkilled sporozoites. Viability or cell death was determined by the addition of fluorescein diacetate (green) (live cells) and propidium iodide (red) (dead cells). Each component was used at 25 ug/ml.
Imboden, M., Riggs, M. W., Schaefer, D. A., Homan, E. J., & Bremel, R. D. (2010). Antibodies fused to innate immune molecules reduce initiation of Cryptosporidium parvum infection in mice. Antimicrobial agents and chemotherapy, 54(4), 1385-1392.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-895 | Recombinant Anti-SEB Antibody | ELISA, IF, FuncS | IgG |
MHH-895 | Recombinant Human Anti-SEB Antibody | WB, Dot, FuncS | IgG |
PABL-336 | Recombinant Human Anti-Staphylococcal enterotoxin B (SEB) Antibody (3E2) | WB, ELISA, Neut, FuncS | IgG |
PABL-337 | Recombinant Mouse Anti-Staphylococcal enterotoxin B (SEB) Antibody (20B1) | Neut, FuncS | IgG |
HPAB-0090-FY | Recombinant Mouse Anti-SEB Antibody (FMU-SEB-No.2) | E |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-895-F(E) | Recombinant Anti-SEB Antibody Fab Fragment | ELISA, FacS, FuncS | Fab |
PFBL-698 | Recombinant Mouse Anti-Staphylococcal enterotoxin B (SEB) Antibody Fab Fragment (14G8) | WB, ELISA, FuncS | Fab |
PFBL-699 | Recombinant Mouse Anti-Staphylococcal enterotoxin B (SEB) Antibody Fab Fragment (6D3) | WB, IF, FuncS | Fab |
PFBL-700 | Recombinant Mouse Anti-Staphylococcal enterotoxin B (SEB) Antibody Fab Fragment (3E2) | ELISA, WB | Fab |
PFBS-0023 | Mouse Anti-Staphylococcal enterotoxin B (SEB) Recombinant Antibody (Clone 4PCL2); Fab Fragment | ELISA, SPR, FuncS | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MHH-895-S(P) | Recombinant Human Anti-SEB Antibody scFv Fragment | ELISA, WB, IP, FuncS | scFv |
PSBL-698 | Recombinant Mouse Anti-Staphylococcal enterotoxin B (SEB) Antibody scFv Fragment (14G8) | WB, ELISA, FuncS | scFv |
PSBL-699 | Recombinant Mouse Anti-Staphylococcal enterotoxin B (SEB) Antibody scFv Fragment (6D3) | WB, IF, FuncS | scFv |
PSBL-700 | Recombinant Mouse Anti-Staphylococcal enterotoxin B (SEB) Antibody scFv Fragment (3E2) | ELISA, WB | scFv |
HPAB-0090-FY-S(P) | Recombinant Mouse Anti-SEB Antibody scFv Fragment (FMU-SEB-No.2) | E |
CAT | Product Name | Application | Type |
---|---|---|---|
PNBL-029 | Recombinant Anti-Staphylococcal SEB VHH Single Domain Antibody (A3) | SPR | Llama VHH |
PNBL-094 | Recombinant Anti-Staphylococcal enterotoxin B (SEB) VHH Single Domain Antibody (S74A) | WB, FuncS | Llama VHH |
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