Anti-Human TCR Recombinant Antibody (C-17) (CAT#: TAB-557CT)
Recombinant monoclonal antibody specifically binds to the extracellular constant domain of the TCR α chain. This antibody can be potentially used in treating T-cell malignancies.
Specific Inquiry
WB
Figure 1 Induction of open CD3 in thymocytes stimulated with anti-TCR–CD3 antibodies.
After cell lysis, antibody C-17 (10 μg/ml) specific for distinct CD3 subunits were added to the lysates and were present during the assay.
Gil, D., Schrum, A. G., Alarcón, B., & Palmer, E. (2005). T cell receptor engagement by peptide–MHC ligands induces a conformational change in the CD3 complex of thymocytes. Journal of Experimental Medicine, 201(4), 517-522.
Specifications
- Host Species
- Humanized
- Type
- Humanized antibody
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- C-17
- Applications
- WB
- Related Disease
- Autoimmune Disease, T-cell malignancies
Applications
- Application Notes
- This antibody has been reported for use in Western Blot.
Target
- Alternative Names
- TCR; T cell receptor; TCRA; TCRB
Related Resources
Asthma
Rheumatoid Arthritis
Systemic Lupus Erythematosus
Allograft Rejection
Autoimmune Thyroid Disease
Graft-versus-Host Disease
Amyotrophic Lateral Sclerosis
Maturity Onset Diabetes of the Young
TCR Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-956 | Recombinant Anti-TCR Antibody | WB, ELISA, IHC, FuncS | IgG |
| HPAB-2571LY | Human Anti-TCR Recombinant Antibody (clone 15B4) | FC, ELISA | Humanized IgG |
| HPAB-2572LY | Human Anti-TCR Recombinant Antibody (clone 5H4) | FC, ELISA | Humanized IgG |
| FAMAB-1511CQ | Mouse Anti-TCR Recombinant Antibody (clone H57-597) | IP, FC, IHC | Mouse IgG1 |
| FAMAB-1512CQ | Mouse Anti-TCR Recombinant Antibody (clone Desire-1) | IP, FC, IF | Mouse IgG1 |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-956-F(E) | Recombinant Anti-TCR Antibody Fab Fragment | WB, IP, FuncS | Fab |
| FAMAB-0109-CN-F(E) | Rat Anti-TCR Recombinant Antibody (clone KJ16); Fab Fragment | ELISA, IF, IP, WB, FC | Rat Fab |
| FAMAB-0110-CN-F(E) | Mouse Anti-TCR Recombinant Antibody (clone 1B2); Fab Fragment | ELISA, WB, FC | Mouse Fab |
| HPAB-2571LY-F(E) | Human Anti-TCR Recombinant Antibody (clone 15B4); Fab Fragment | FC, ELISA | Humanized Fab |
| HPAB-2572LY-F(E) | Human Anti-TCR Recombinant Antibody (clone 5H4); Fab Fragment | FC, ELISA | Humanized Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-956-S(P) | Recombinant Human Anti-TCR Antibody scFv Fragment | FC, ELISA, FuncS | scFv |
| TAB-558CT-S(P) | Hamster Anti-TCR Recombinant Antibody (clone H57); scFv Fragment | WB, FC | Hamster scFv |
| FAMAB-0109-CN-S(P) | Rat Anti-TCR Recombinant Antibody (clone KJ16); scFv Fragment | ELISA, IF, IP, WB, FC | Rat scFv |
| FAMAB-0110-CN-S(P) | Mouse Anti-TCR Recombinant Antibody (clone 1B2); scFv Fragment | ELISA, WB, FC | Mouse scFv |
| HPAB-2571LY-S(P) | Human Anti-TCR Recombinant Antibody (clone 15B4); scfv Fragment | FC, ELISA | Humanized scfv |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-595CL | Mouse Anti-TCR Recombinant Antibody (TAB-595CL) | FuncS | Mouse IgG |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-545CT | Anti-Human TCR Recombinant Antibody (BMA 031) | FC | Humanized antibody |
| TAB-546CT | Anti-Human TCR Recombinant Antibody (3H2906) | ELISA, FC, WB | Humanized antibody |
| TAB-547CT | Anti-Human TCR Recombinant Antibody (IP26) | WB | Humanized antibody |
| TAB-548CT | Anti-Human TCR Recombinant Antibody (T10B9) | FC, Cyt, Inhib | Humanized antibody |
| TAB-549CT | Anti-Human TCR Recombinant Antibody (WT31) | Inhib | Humanized antibody |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-248 | Afuco™ Anti-TCR ADCC Recombinant Antibody (Maslimomab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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