Recombinant Anti-human TERT Intrabody [(D-Arg)9] (CAT#: IAB-B046(A))

Recombinant anti-TERT intrabody linked to (D-Arg)9 works within cells and specifically reacts with human TERT, expressed in CHO cells. The intrabody can directed against hTERT to attenuate the immortalization of human uterine cervix and hepatoma cells.


Specific Inquiry
  • Size:
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  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression

Specifications

  • Immunogen
  • human telomerase reverse transcriptase
  • Host Species
  • human
  • Type
  • scFv-(D-Arg)9
  • Cell Penetrating Peptide
  • (D-Arg)9
    It has been proven that polyarginine peptides composed of nine arginine amino acids (Arg-9) are able to translocate across cells very efficiently. This raises the question if molecular dynamics simulations would show a similar pathway for this highly hydrophilic and charged peptide as predicted for the Tat peptide. The simplicity of Arg-9 over other CPPs also helps isolate the role of the Arg sidechain on the translocation without the effect of other sidechains. Therefore, in this work we study computationally the translocation of Arg-9 through a lipid bilayer and show that the translocation mechanism is the same as for the Tat peptide.
  • Species Reactivity
  • human
  • Applications
  • Used for immunoassay techniques such as: Protein fragment complementation; Neutralization; Functional studies

Product Property

  • Purity
  • >95% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE
  • Storage
  • 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.

Target

  • Alternative Names
  • TERT; telomerase reverse transcriptase; TP2; TRT; CMM9; EST2; TCS1; hTRT; DKCA2; DKCB4; hEST2; PFBMFT1; telomerase catalytic subunit; telomerase-associated protein 2

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "TERT"

Fab Fragment Antibody

scFv Fragment Antibody

Single-domain Antibody

CAT Product Name Application Type
NABL-050 Recombinant Anti-human TERT VHH Single Domain Antibody WB, ELISA, IP, FuncS Llama VHH

Intrabody

CAT Product Name Application Type
IAB-B046(G) Recombinant Anti-human TERT Intrabody [+36 GFP] WB, Neut, FuncS scFv-(+36GFP)
IAB-B046(T) Recombinant Anti-human TERT Intrabody [Tat] WB, ICC, Neut, FuncS scFv-Tat

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0581MZ Chicken Anti-TERT Polyclonal IgY WB Chicken antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-3533 Rabbit Anti-TERT Recombinant Antibody (clone DS3533AB) FC, ICC, IF, IHC-Fr, IHC-P, IP, WB Rabbit IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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