Mouse Anti-TF Recombinant Antibody (clone JAA-F11); scFv Fragment (CAT#: PSBW-164)

Recombinant Mouse Antibody (JAA-F11) scFv Fragment is specific to TF antigen(Galβ1-3GalNAcα), expressed in E. coli. JAA-F11 preferentially binds to tumor tissue over normal, and in vivo it enhances survival and decreases metastasis in the mouse 4T1 metastatic model, indicating a potential for this mAb to be used, after humanization, in cancer patient therapy.


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SDS-PAGE

Figure 1 Mouse Anti-TF Recombinant Antibody; scFv Fragment (PSBW-164) in SDS-PAGE

Figure 1 Mouse Anti-TF Recombinant Antibody; scFv Fragment (PSBW-164) in SDS-PAGE

Lane M: Protein Marker
Lane 1: 0.5 mg/mL BSA
Lane 2: PSBW-164


Specifications

  • Immunogen
  • Human Thomsen-Friedenreich antigen (Galβ1-3GalNAcα)
  • Host Species
  • Mouse
  • Type
  • Mouse scFv
  • Specificity
  • Human TF
  • Species Reactivity
  • Human
  • Clone
  • JAA-F11
  • Applications
  • FuncS

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Galβ1-3GalNAcα; Thomsen-Friedenreich; TF

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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See other products for "Clone JAA-F11"

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Humanized Antibody

Deglycosylated Antibody (Non-glycosylated IgGs)

CAT Product Name Application Type
Gly-175LC Recombinant Anti-Human TF Antibody (Non-glycosylated) ELISA Mouse antibody

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0860MZ Chicken Anti-Transferrin Polyclonal IgY ELISA Chicken antibody

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1996CQ Mouse Anti-TF Recombinant Antibody (clone HTF-14) WB, Neut, ELISA, ICC, IF, IHC, IHC-P, RIA Mouse IgG1

Blocking Antibody

CAT Product Name Application Type
NEUT-2022CQ Mouse Anti-TF Recombinant Antibody (clone A68-B/A11) ELISA, Inhib, IHC-P, IHC-Fr Mouse IgM

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-3535 Rabbit Anti-TF Recombinant Antibody (clone DS3535AB) IHC-P, IP, WB Rabbit IgG

Recombinant Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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