This immunotoxin was achieved by conjugating/fusing the Anti-TFRC scFv to Pseudomonas exotoxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to tumor cells. Once bind, the toxin enters cells by receptor-mediated endocytosis. Then PE cleaved fragments the size of Mr 37000 and 27000, the large fragment and finally into the Golgi and elongation factor 2 (EM) combining it glycosylation inactivation, inhibition of protein synthesis, leading to apoptosis. It was designed for treating malignant.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1176z-S(P) | Recombinant Anti-Human TFRC Antibody scFv Fragment | ELISA, WB, IF, FuncS | scFv |
MOB-035LC-S(P) | Rat Anti-TFRC Recombinant Antibody (clone 9E4); scFv Fragment | FuncS, IHC, FC | Rat scFv |
HPAB-0238-YJ-S(P) | Rat Anti-TFRC Recombinant Antibody; scFv Fragment (HPAB-0238-YJ-S(P)) | IHC, FC, WB, FuncS | Rat scFv |
HPAB-0239-YJ-S(P) | Rat Anti-TFRC Recombinant Antibody; scFv Fragment (HPAB-0239-YJ-S(P)) | IHC, FC, WB, FuncS | Rat scFv |
HPAB-0240-YJ-S(P) | Rat Anti-TFRC Recombinant Antibody; scFv Fragment (HPAB-0240-YJ-S(P)) | IHC, FC, WB, FuncS | Rat scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-G067D | Anti-TFRC immunotoxin HB21 (scFv)-DT | Cytotoxicity assay, Function study | |
AGTO-G067G | Anti-TFRC immunotoxin HB21 (scFv)-Gel | Cytotoxicity assay, Function study | |
AGTO-G067R | Anti-TFRC immunotoxin HB21 (scFv)-RTA | Cytotoxicity assay, Function study | |
AGTO-G067S | Anti-TFRC immunotoxin HB21 (scFv)-Sap | Cytotoxicity assay, Function study | |
AGTO-G068E | Anti-TFRC immunotoxin 454A12 (IgG)-PE | Cytotoxicity assay, Function study |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0464CL | Mouse Anti-TFRC Recombinant Antibody (TAB-0464CL) | FuncS | Mouse IgG |
TAB-0465CL | Mouse Anti-TFRC Recombinant Antibody (TAB-0465CL) | FuncS | Mouse IgG |
TAB-0466CL | Mouse Anti-TFRC Recombinant Antibody (TAB-0466CL) | FuncS | Mouse IgG |
TAB-0464CL-S(P) | Mouse Anti-TFRC Recombinant Antibody; scFv Fragment (TAB-0464CL-S(P)) | FuncS | Mouse scFv |
TAB-0465CL-S(P) | Mouse Anti-TFRC Recombinant Antibody; scFv Fragment (TAB-0465CL-S(P)) | FuncS | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-611CT | Humanized Anti-TFRC Recombinant Antibody (TAB-611CT) | ELISA | Humanized IgG |
TAB-612CT | Humanized Anti-TFRC Recombinant Antibody (TAB-612CT) | ELISA | Humanized IgG |
TAB-613CT | Humanized Anti-TFRC Recombinant Antibody (TAB-613CT) | ELISA | Humanized IgG |
TAB-614CT | Humanized Anti-TFRC Recombinant Antibody (TAB-614CT) | ELISA | Humanized IgG |
TAB-611CT-F(E) | Humanized Anti-TFRC Recombinant Antibody; Fab Fragment (TAB-611CT-F(E)) | ELISA | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-619CT-S(P) | Human Anti-TFRC Recombinant Antibody; scFv Fragment (TAB-619CT-S(P)) | ELISA, WB | Human scFv |
TAB-620CT-S(P) | Human Anti-TFRC Recombinant Antibody; scFv Fragment (TAB-620CT-S(P)) | ELISA, WB | Human scFv |
TAB-621CT-S(P) | Anti-Human TfR Recombinant Antibody scFv Fragment (LUCA31) | ELISA, WB, FC | Human antibody |
TAB-623CT-S(P) | Anti-Human TfR Recombinant Antibody scFv Fragment (3TF12) | WB | Human antibody |
TAB-624CT-S(P) | Anti-Human TfR Recombinant Antibody scFv Fragment (3TF2) | WB | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1999CQ | Rat Anti-Tfrc Recombinant Antibody (clone RI7217) | FC, ICC, IP, WB, Block | Rat IgG2a, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-3548 | Rabbit Anti-TFRC Recombinant Antibody (clone DS3548AB) | FC, IP, WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC3370 | PE-DRB1*13:02/Human TFRC (NPGGYVAYSKAATVTGKL) MHC Tetramer | FCM | |
MHC-LC3371 | PE-DRB1*13:02/Human TFRC (NPGGYVAYSKAATVTG) MHC Tetramer | FCM |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0376-CN | Mouse Anti-TFRC Recombinant Antibody (HPAB-0376-CN) | ELISA, FC | Mouse IgG |
HPAB-0377-CN | Mouse Anti-TFRC Recombinant Antibody (HPAB-0377-CN) | ELISA, FC | Mouse IgG |
HPAB-0378-CN | Mouse Anti-TFRC Recombinant Antibody (HPAB-0378-CN) | ELISA, FC | Mouse IgG |
HPAB-0379-CN | Human Anti-TFRC Recombinant Antibody (HPAB-0379-CN) | ELISA, FC | Humanized IgG |
HPAB-0380-CN | Mouse Anti-TFRC Recombinant Antibody (clone BA120G) | ELISA, FC, IF, IP | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0238-YJ-F(E) | Rat Anti-TFRC Recombinant Antibody; Fab Fragment (HPAB-0238-YJ-F(E)) | IHC, FC, WB, FuncS | Rat Fab |
HPAB-0239-YJ-F(E) | Mouse Anti-TFRC Recombinant Antibody; Fab Fragment (HPAB-0239-YJ-F(E)) | IHC, FC, WB, FuncS | Mouse Fab |
HPAB-0240-YJ-F(E) | Mouse Anti-TFRC Recombinant Antibody; Fab Fragment (HPAB-0240-YJ-F(E)) | IHC, FC, WB, FuncS | Mouse Fab |
HPAB-2692LY-F(E) | Mouse Anti-TFRC Recombinant Antibody; Fab Fragment (HPAB-2692LY-F(E)) | ELISA | Mouse Fab |
HPAB-2693LY-F(E) | Mouse Anti-TFRC Recombinant Antibody; Fab Fragment (HPAB-2693LY-F(E)) | ELISA | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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