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Anti-TGM2 Intrabody [+36GFP] (IAB-B010(G))

Recombinant anti-TGM2 intrabody in fusion with +36GFP works within cells and directes to antigen human TGM2, expressed in CHO cells. The intracellular antibody can inhibit the ransglutaminase activity may be by one or more techniques, including, but not limited to, downregulating transglutaminase expression, inhibiting TG2 translation, or blocking TG2 enzymatic activity.      

Specifications
Immunogen
human transglutaminase 2
Host
mouse
Type
scFv-(+36GFP)
Cell Penetrating Peptide
+36 GFP
GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
Species Reactivity
human
Applications
Antibody assay: Protein fragment complementation; Western blot; Functional studies
Target
Alternative Names
TGM2; transglutaminase 2; TG2; TGC; GNAH; HEL-S-45; G-ALPHA-h; protein-glutamine gamma-glutamyltransferase 2
Entrez Gene ID
7052
UniProt ID
P21980

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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