This immunotoxin was achieved by conjugating/fusing the Anti-THY1 F(ab')2 to ricin toxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to THY 1-expressing cells. Then the ricin A chain is incorporated into the cell by receptor-mediated endocytosis, blocking ribosomal protein synthesis and ultimately leading to cell death. It was designed for treatment of lymphoma.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1495z-F(E) | Recombinant Anti-Human THY1 Antibody Fab Fragment | FC, WB, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-G060S | Anti-THY1 immunotoxin OX7 (F (ab')2)-Sap | Cytotoxicity assay, Function study | |
AGTO-L040R | anti-THY1 immunotoxin AT15E (IgG)-RTA | Cytotoxicity assay, Functional assay | |
AGTO-L040S | anti-THY1 immunotoxin AT15E (IgG)-Sap | Cytotoxicity assay, Functional assay | |
AGTO-L060S | anti-Thy1 immunotoxin OX7 (IgG)-Sap | Cytotoxicity assay, Functional assay |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-2023CQ | Rat Anti-THY1 Recombinant Antibody (clone YKIX337.217) | Block, FC | Rat IgG2b |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-3568 | Rabbit Anti-THY1 Recombinant Antibody (clone DS3568AB) | ICC, IHC-P, WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-0322-CN | Rabbit Anti-THY1 Recombinant Antibody (clone CBACN-124) | WB, IHC, IF | Rabbit IgG |
MRO-1491-CN | Rabbit Anti-THY1 Recombinant Antibody (clone JF10-09) | WB, IF, IHC | Rabbit IgG |
FN-266CQ | Rat Anti-Thy1 Recombinant Antibody (clone M5/49.4.1) | Depletion | Rat IgG2a, κ |
FAMAB-1676CQ | Mouse Anti-THY1 Recombinant Antibody (clone T11D7e) | Depletion, IF | Mouse IgG1 |
VS3-XY1516 | Mouse Anti-THY1 Recombinant Antibody, FITC (clone 4AeBio5E10) | IF, FC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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