Anti-Human TMEFF2 Recombinant Antibody (AT-19) (CAT#: TAB-158CQ)
The human monoclonal antibody binds to TMEFF2. The antibody was expressed in mammalian cells with chemically defined culture media and was purified by affinity chromatography.
Specific Inquiry
FC
Figure 1 Fluorescence-activated cell sorting (FACS) binding by high concentrations of Alexa 488–labeled AT-19 monovalent ("helper") and AT-19 multivalent ("hyper") phage particles to tomoregulin (TR)– expressing CHO-TR and control CHO-K1 cells.
Heitner, T., Satozawa, N., Mclean, K., Vogel, D., Cobb, R. R., Liu, B., ... & Zhou, H. (2006). Obligate multivalent recognition of cell surface tomoregulin following selection from a multivalent phage antibody library. Journal of biomolecular screening, 11(8), 985-995.
ELISA
Figure 2 Measurement of AT-19 single-chain variable fragment (scFv) binding in the live-cell enzyme-linked immunosorbent assay (ELISA) and immune complex ELISA (ICELISA).
Live-cell ELISA with purified scFv on tomoregulin (TR)–expressing PC-3–TR clone 69 (left). Binding of the monovalent scFv to native TR in a standard cell-based ELISA is similar to nonspecific binding by a control scFv at concentrations of 5 µg/mL (200 nM), 1 µg/mL (40 nM), and 0.2 µg/mL (8 nM).
Heitner, T., Satozawa, N., Mclean, K., Vogel, D., Cobb, R. R., Liu, B., ... & Zhou, H. (2006). Obligate multivalent recognition of cell surface tomoregulin following selection from a multivalent phage antibody library. Journal of biomolecular screening, 11(8), 985-995.
Specifications
- Host Species
- Human
- Derivation
- Human naϊve antibody phage display library
- Type
- Human antibody
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- AT-19
- Applications
- ELISA, FC, IF
- Related Disease
- Prostate cancer
Applications
- Application Notes
- This antibody has been tested for use in ELISA, Flow Cytometry, Immunofluorescence. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- TMEFF2; Transmembrane protein with EGF-like and two follistatin-like domains 2; TR; HPP1; TPEF; TENB2; CT120.2; tomoregulin-2; TR-2; tomoregulin; transmembrane protein TENB2; hyperplastic polyposis protein 1; cancer/testis antigen family 120, member 2
- Gene ID
- 23671
- UniProt ID
- Q9UIK5
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3543z | Mouse Anti-TMEFF2 Recombinant Antibody (MOB-3543z) | ELISA, IHC, WB, IF | Mouse IgG |
| HPAB-0022-LS | Mouse Anti-TMEFF2 Recombinant Antibody (clone TMEFF2#19) | ELISA | Humanized lgG |
| VS4-CJ136 | Recombinant Human Anti-TMEFF2 Antibody (clone 6G6) | ELISA | Human IgG4 (S228P) |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3543z-F(E) | Recombinant Anti-Human TMEFF2 Antibody Fab Fragment | IF, FuncS | Fab |
| HPAB-0022-LS-F(E) | Mouse Anti-TMEFF2 Recombinant Antibody (clone TMEFF2#19); Fab Fragment | ELISA | Humanized Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-3543z-S(P) | Recombinant Anti-Human TMEFF2 Antibody scFv Fragment | ELISA, WB, FuncS | scFv |
| HPAB-0022-LS-S(P) | Mouse Anti-TMEFF2 Recombinant Antibody (clone TMEFF2#19); scFv Fragment | ELISA | Humanized scFv |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0284CL | Anti-Human TMEFF2 Recombinant Antibody (PQ01 (#001)) | ELISA, WB, FuncS | |
| TAB-0284CL-S(P) | Anti-Human TMEFF2 Recombinant Antibody scFv Fragment (PQ01 (#001)) | ELISA, WB, FuncS | |
| TAB-0284CL-F(E) | Anti-Human TMEFF2 Recombinant Antibody Fab Fragment (PQ01 (#001)) | ELISA, WB, FuncS |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-594CT | Humanized Anti-TMEFF2 Recombinant Antibody (TAB-594CT) | ELISA, FC, IHC | Humanized antibody |
| TAB-594CT-S(P) | Humanized Anti-TMEFF2 Recombinant Antibody; scFv Fragment (TAB-594CT-S(P)) | ELISA, FC, IHC | Humanized scFv |
| TAB-594CT-F(E) | Humanized Anti-TMEFF2 Recombinant Antibody; Fab Fragment (TAB-594CT-F(E)) | ELISA, FC, IHC | Humanized Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-158CQ-S(P) | Anti-Human TMEFF2 Recombinant Antibody scFv Fragment (AT-19) | ELISA, FC, IF | Human antibody |
| TAB-158CQ-F(E) | Anti-Human TMEFF2 Recombinant Antibody Fab Fragment (AT-19) | ELISA, FC, IF | Human antibody |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3590 | Rabbit Anti-TMEFF2 Recombinant Antibody (clone DS3590AB) | WB | Rabbit IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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