Anti-Human TNF Recombinant Antibody (YHB1411-2) (CAT#: TAB-118CQ)

The human antibody exhibits a high antigen binding affinity of picomole level and a low dissociation constant. It can be effectively used for treating a hTNF-α-related diseases such as rheumatoid arthritis.


Specific Inquiry
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  • Purity:
  • Fc Engineering:
  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
FC

Figure 1 Binding activity of the antagonists for yeast surface-displayed, (a) native and (b) heat-denatured wildtype TNFα, monitored by flow cytometry.

Figure 1 Binding activity of the antagonists for yeast surface-displayed, (a) native and (b) heat-denatured wildtype TNFα, monitored by flow cytometry.

Kim, M. S., Lee, S. H., Song, M. Y., Yoo, T. H., Lee, B. K., & Kim, Y. S. (2007). Comparative analyses of complex formation and binding sites between human tumor necrosis factor-alpha and its three antagonists elucidate their different neutralizing mechanisms. Journal of molecular biology, 374(5), 1374-1388.


Specifications

  • Host Species
  • Human
  • Type
  • Humanized antibody
  • Specificity
  • Human
  • Species Reactivity
  • Human
  • Clone
  • YHB1411-2
  • Applications
  • FC, ELISA
  • Related Disease
  • Rheumatoid arthritis

Applications

  • Application Notes
  • This antibody has been tested for use in Flow Cytometry, ELISA. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.

Target

  • Alternative Names
  • TNF; DIF; TNFA; TNFSF2; TNF-alpha; TNLG1F; Tumor necrosis factor

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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Chimeric Antibody

CAT Product Name Application Type
TAB-006 Anti-Human TNF Recombinant Antibody (Infliximab) IF, IP, Neut, FuncS, ELISA, FC, WB IgG1 - kappa
TAB-148CQ Anti-Human TNF Recombinant Antibody ELISA Chimeric antibody (mouse/human)
TAB-148CQ-S(P) Anti-Human TNF Recombinant Antibody scFv Fragment ELISA Chimeric antibody (mouse/human)
TAB-402CQ-S(P) Mouse Anti-TNF Recombinant Antibody; scFv Fragment (TAB-402CQ-S(P)) ELISA Mouse scFv
TAB-402CQ-F(E) Human Anti-TNF Recombinant Antibody; Fab Fragment (TAB-402CQ-F(E)) ELISA Chimeric (mouse/human) Fab

Humanized Antibody

CAT Product Name Application Type
TAB-034-F(E) Anti-Human TNF alpha Recombinant Antibody Fab Fragment (Certolizumab Pegol) ELISA, FC, IP, FuncS, IF, Neut, IHC Fab'
TAB-110CQ Anti-Human TNF Recombinant Antibody (CDP571) ELISA Humanized antibody
TAB-114CQ Human Anti-TNF Recombinant Antibody (TAB-114CQ) ELISA, FC, Inhib Humanized antibody
TAB-115CQ Human Anti-TNF Recombinant Antibody (TAB-115CQ) ELISA, FC, Neut Humanized antibody
TAB-124CQ Human Anti-TNF Recombinant Antibody (TAB-124CQ) FuncS, Neut Humanized antibody

Rat Antibody

CAT Product Name Application Type
TAB-623CL Bovine Anti-TNF Recombinant Antibody (TAB-623CL) Neut Bovine IgG

Non-hyper Galactosylated

CAT Product Name Application Type
Gly-083LC-1 Recombinant Anti-Human TNF Antibody (Fc glycosylation/Non-hyper galactosylated) ELISA, FC Human antibody

Sialylated IgG Glycan

CAT Product Name Application Type
Gly-085LC-1 Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) ELISA, FC Human antibody
Gly-163LC-1 Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) ELISA Chimeric antibody (mouse/human)

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0609MZ Chicken Anti-Tumor Necrosis Factor-α Polyclonal IgY Indirect ELISA, WB Chicken antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-2057CQ Rat Anti-Tnf Recombinant Antibody (clone XT3) Block, ELISA, IHC, WB Rat IgG1
NEUT-2070CQ Mouse Anti-TNF Recombinant Antibody (clone 4F4) Block, ELISA, ICC, IF, IHC, WB Mouse IgG1
NEUT-2071CQ Rabbit Anti-TNF Recombinant Antibody (clone 6E10) Block, ELISA, IHC, WB Rabbit IgG1
NEUT-2082CQ Mouse Anti-TNF Recombinant Antibody (clone B-C7) Block Mouse IgG1

Neutralizing Antibody

CAT Product Name Application Type
NEUT-2094CQ Mouse Anti-TNF Recombinant Antibody (clone CBL956) ELISA, Neut Mouse IgG1, κ
NEUT-2095CQ Mouse Anti-TNF Recombinant Antibody (clone CBL957) ELISA, Neut, IHC Mouse IgG1, κ
NEUT-2096CQ Mouse Anti-TNF Recombinant Antibody (clone CBL959) ELISA, ICC, Neut, WB Mouse IgG1
NEUT-2097CQ Mouse Anti-TNF Recombinant Antibody (clone CBL965) ELISA, IHC, Neut, WB Mouse IgG1, κ
NEUT-2108CQ Mouse Anti-TNF Recombinant Antibody (clone mAb11) ELISA, CyTOF, FC, ICFC, ICC, IF, IHC, Neut Mouse IgG1, κ

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-768 Afuco™ Anti-TNF ADCC Recombinant Antibody (Nerelimomab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC, IP ADCC enhanced antibody
AFC-TAB-006 Afuco™ Anti-TNF ADCC Recombinant Antibody (Infliximab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody
AFC-TAB-010 Afuco™ Anti-TNF ADCC Recombinant Antibody (AFC-TAB-010), ADCC Enhanced FC, IP, ELISA, Neut, FuncS ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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