Anti-Human TNF Recombinant Antibody (ADB-SAlg) (CAT#: TAB-122CQ)

The monoclonal secretory IgA antibody binds to and neutralizes human TNFα. The secretory antibody is useful in treating a variety of inflammatory diseases.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
ELISA

Figure 1 shows binding curves of antibodies to TNFa.

Figure 1 shows binding curves of antibodies to TNFa.

The closed circle represents a SAlg having infliximab variable regions, square represents infliximab, and diamond represents colostral secretory IgA.

FuncS

Figure 2 shows TNFa-induced disturbance of Caco-2 monolayer integrity as measured by transepithelial electrical resistance (TER).

Figure 2 shows TNFa-induced disturbance of Caco-2 monolayer integrity as measured by transepithelial electrical resistance (TER).

FuncS

Figure 3 represents the colitis scoring of DSS-induced inflammatory bowel disease in C57BL/6 mice with and without treatment.

Figure 3 represents the colitis scoring of DSS-induced inflammatory bowel disease in C57BL/6 mice with and without treatment.

FuncS

Figure 4 shows the effects of subcutaneous application of etanercept and of oral application of ADB-SAlg on gripping strength of a transgenic TNFa-overexpressing.

Figure 4 shows the effects of subcutaneous application of etanercept and of oral application of ADB-SAlg on gripping strength of a transgenic TNFa-overexpressing.

FuncS

Figure 5 shows the effects of subcutaneous application of etancercept and of oral application of ADB-SAlg on arthritic score of hind paws of transgenic TNFa.

Figure 5 shows the effects of subcutaneous application of etancercept and of oral application of ADB-SAlg on arthritic score of hind paws of transgenic TNFa.


Specifications

  • Host Species
  • Human
  • Type
  • Human antibody
  • Specificity
  • Human
  • Species Reactivity
  • Human
  • Clone
  • ADB-SAlg
  • Applications
  • ELISA, FuncS
  • Related Disease
  • Inflammatory diseases

Applications

  • Application Notes
  • This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Functional Assay.

Target

  • Alternative Names
  • TNF; DIF; TNFA; TNFSF2; TNF-alpha; TNLG1F; Tumor necrosis factor

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone ADB-SAlg"

See other products for "TNF"

Rat Antibody

CAT Product Name Application Type
TAB-623CL Bovine Anti-TNF Recombinant Antibody (TAB-623CL) Neut Bovine IgG

Humanized Antibody

CAT Product Name Application Type
TAB-124CQ Human Anti-TNF Recombinant Antibody (TAB-124CQ) FuncS, Neut Humanized antibody
TAB-125CQ Human Anti-TNF Recombinant Antibody (TAB-125CQ) ELISA, Neut Humanized antibody
TAB-126CQ Human Anti-TNF Recombinant Antibody (TAB-126CQ) ELISA, Neut Humanized antibody
TAB-127CQ Human Anti-TNF Recombinant Antibody (TAB-127CQ) ELISA, Neut Humanized antibody
TAB-128CQ Human Anti-TNF Recombinant Antibody (TAB-128CQ) ELISA, FuncS Humanized antibody

Chimeric Antibody

Non-hyper Galactosylated

CAT Product Name Application Type
Gly-083LC-1 Recombinant Anti-Human TNF Antibody (Fc glycosylation/Non-hyper galactosylated) ELISA, FC Human antibody

Sialylated IgG Glycan

CAT Product Name Application Type
Gly-085LC-1 Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) ELISA, FC Human antibody
Gly-163LC-1 Recombinant Anti-Human TNF Antibody (Fc glycosylation/Sialylated) ELISA Chimeric antibody (mouse/human)

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0609MZ Chicken Anti-Tumor Necrosis Factor-α Polyclonal IgY Indirect ELISA, WB Chicken antibody

Blocking Antibody

CAT Product Name Application Type
NEUT-2057CQ Rat Anti-Tnf Recombinant Antibody (clone XT3) Block, ELISA, IHC, WB Rat IgG1
NEUT-2070CQ Mouse Anti-TNF Recombinant Antibody (clone 4F4) Block, ELISA, ICC, IF, IHC, WB Mouse IgG1
NEUT-2071CQ Rabbit Anti-TNF Recombinant Antibody (clone 6E10) Block, ELISA, IHC, WB Rabbit IgG1
NEUT-2082CQ Mouse Anti-TNF Recombinant Antibody (clone B-C7) Block Mouse IgG1

Recombinant Antibody

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-768 Afuco™ Anti-TNF ADCC Recombinant Antibody (Nerelimomab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC, IP ADCC enhanced antibody
AFC-TAB-006 Afuco™ Anti-TNF ADCC Recombinant Antibody (Infliximab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody
AFC-TAB-010 Afuco™ Anti-TNF ADCC Recombinant Antibody (AFC-TAB-010), ADCC Enhanced FC, IP, ELISA, Neut, FuncS ADCC enhanced antibody

Customer Reviews and Q&As

Submit a review or a question
There are currently no Customer reviews or questions for TAB-122CQ. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

© 2024 Creative Biolabs.
  • 0
  • 0
Cart

    Go to compare