Anti-Human TNFRSF10A Recombinant Antibody (4E7.24.3) (CAT#: TAB-162CQ)

The antibody binds to DR4, but not to any of the other Apo-2L receptors, Apo-2, DcRl, or DcR2. It can be potentially used in the treatment of various diseases and pathological conditions, including cancer.


Specific Inquiry
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  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
FC

Figure 1 The FACS analysis of two anti-DR4 antibodies, 4E7.24.3 (

Figure 1 The FACS analysis of two anti-DR4 antibodies, 4E7.24.3 ("4E7") and 4H6.17.8 ("4H6") (illustrated by the bold lines) as compared to IgG controls (dotted lines).

ELISA

Figure 2 Results of an ELISA testing binding of DR4 antibodies, 4E7.24.3 and 4H6.17.8, to DR4 and to other known Apo-2L receptors referred to as Apo-2, DcR1, and DcR2.

Figure 2 Results of an ELISA testing binding of DR4 antibodies, 4E7.24.3 and 4H6.17.8, to DR4 and to other known Apo-2L receptors referred to as Apo-2, DcR1, and DcR2.


Specifications

  • Immunogen
  • A soluble DR4 ECD
  • Host Species
  • Mouse
  • Specificity
  • Human
  • Species Reactivity
  • Human
  • Clone
  • 4E7.24.3
  • Applications
  • FC, ELISA, Block
  • Related Disease
  • Lupus, herpes virus infection and so on

Applications

  • Application Notes
  • This antibody has been tested for use in Flow Cytometry, ELISA, Blocking. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.

Target

  • Alternative Names
  • TNFRSF10A; tumor necrosis factor receptor superfamily, member 10a; DR4; APO2; CD261; TRAILR1; TRAILR-1; tumor necrosis factor receptor superfamily member 10A; TRAIL-R1; TRAIL receptor 1; death receptor 4; cytotoxic TRAIL receptor; TNF-related apoptosis-inducing ligand receptor 1; tumor necrosis factor receptor superfamily member 10a variant 2

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 4E7.24.3"

See other products for "TNFRSF10A"

Neutralizing Antibody

CAT Product Name Application Type
NEUT-2109CQ Mouse Anti-TNFRSF10A Recombinant Antibody (clone 32A1380) FC, IHC, Neut, WB Mouse IgG1

Rabbit Monoclonal Antibody

Single-domain Antibody

CAT Product Name Application Type
HPAB-0627-CN Camelid Anti-TNFRSF10A Recombinant Antibody (HPAB-0627-CN) ELISA VHH

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-H48 Afuco™ Anti-TNFRSF10A ADCC Recombinant Antibody (Mapatumumab), ADCC Enhanced Neut, ELISA, IF, IP, FuncS, FC ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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