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Anti-TNFRSF21 Therapeutic Antibody (5D10) (TAB-108CQ)

The antibody binds to human DR6 and blocks the interaction of DR6 and p75. It can inhibit death of cells of the nervous system and can be potentially useful for the treatment in motor neuron diseases.      

Specifications
Host
Mouse
Specificity
Human
Species Reactivity
Human, Cynomolgus monkey, Rat
Clone
5D10
Applications
Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Flow Cytometry; Immunohistochemistry; Western Blot; Immunoprecipitation
Related Disease
Motor neuron diseases
Target
Alternative Names
TNFRSF21; tumor necrosis factor receptor superfamily, member 21; DR6; CD358; BM-018; tumor necrosis factor receptor superfamily member 21; death receptor 6; TNFR-related death receptor 6
Entrez Gene ID
27242
UniProt ID
O75509

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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