Recombinant Human monoclonal antibody expressed in CHO binding to Human TNFRSF21. DQM3 is a functional agonist monoclonal antibody against DR6, which bound to the first cysteine-rich domain. Death receptor 6 (DR6) is a member of the death domain-containing receptors that belong to the TNFR superfamily.
Figure 1 DQM3 stimulates DR6-induced IL-6 luciferase activity.
HEK293T cells were co-transfected with DR6-FL, IL-6 luciferase reporter and Renilla. Anti-DR6 mAbs (DQM2, DQM3 and DQM5, 10 lg/ml) were added 24 h after transfection, and isotype control antibody alone also served as a negative control. Luciferase assays were performed to measure promoter activity after 16 h of antibody incubation.
Hu, R., Du, Q., Yin, X., Li, J., Wang, T., & Zhang, L. (2014). Agonist antibody activates death receptor 6 downstream signaling involving TRADD recruitment. FEBS letters, 588(3), 401-407.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-984 | Recombinant Anti-human TNFRSF21 Antibody | ELISA, WB, FuncS | IgG |
MHH-984 | Recombinant Human Anti-human TNFRSF21 Antibody | IF, FC, FuncS | IgG |
MOB-2092MZ | Recombinant Mouse Anti-Human TNFRSF21 Antibody (clone ES-7-05-FD) | FC, ICC/IF, IP | Mouse antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-984-F(E) | Recombinant Anti-human TNFRSF21 Antibody Fab Fragment | RIA, IP, FuncS | Fab |
MHH-984-F(E) | Recombinant Human Anti-human TNFRSF21 Antibody Fab Fragment | WB, IF, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-984-S(P) | Recombinant Anti-human TNFRSF21 Antibody scFv Fragment | ELISA, IP, FuncS | scFv |
MHH-984-S(P) | Recombinant Human Anti-human TNFRSF21 Antibody scFv Fragment | WB, Neut, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-108CQ-S(P) | Mouse Anti-TNFRSF21 Recombinant Antibody; scFv Fragment (TAB-108CQ-S(P)) | ELISA, FC, IHC, WB, IP | Mouse scFv |
TAB-108CQ-F(E) | Mouse Anti-TNFRSF21 Recombinant Antibody; Fab Fragment (TAB-108CQ-F(E)) | ELISA, FC, IHC, WB, IP | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-109CQ-S(P) | Human Anti-TNFRSF21 Recombinant Antibody; scFv Fragment (TAB-109CQ-S(P)) | ELISA, FC, IHC, WB, IP | Human scFv |
TAB-109CQ-F(E) | Human Anti-TNFRSF21 Recombinant Antibody; Fab Fragment (TAB-109CQ-F(E)) | ELISA, FC, IHC, WB, IP | Human Fab |
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