This immunotoxin was achieved by conjugating/fusing the Anti-TNP monoclonal antibody to ricin toxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to trinitrophenol labeled target cells. Then the ricin A chain is incorporated into the cell by receptor-mediated endocytosis, blocking ribosomal protein synthesis and ultimately leading to cell death. It was designed for treatment of lymphoma.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0286YC | Recombinant Salmon Anti-TNP Antibody (1-01) | ELISA | Salmon IgG |
FAMAB-0287YC | Mouse Anti-TNP Recombinant Antibody (clone IGELa2) | ELISA | Mouse IgE |
FAMAB-0288YC | Mouse Anti-TNP Recombinant Antibody (clone IGELb4) | FuncS | Mouse IgE |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0286-YC-S(P) | Recombinant Salmon Anti-TNP Antibody scFv Fragment (1-01) | ELISA | Salmon scFv |
FAMAB-0287-YC-S(P) | Mouse Anti-TNP Recombinant Antibody (clone IGELa2); scFv Fragment | ELISA | Mouse scFv |
FAMAB-0288-YC-S(P) | Mouse Anti-TNP Recombinant Antibody (clone IGELb4); scFv Fragment | ELISA | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0286-YC-F(E) | Recombinant Salmon Anti-TNP Antibody Fab Fragment (1-01) | ELISA | Salmon Fab |
FAMAB-0287-YC-F(E) | Mouse Anti-TNP Recombinant Antibody (clone IGELa2); Fab Fragment | ELISA | Mouse Fab |
FAMAB-0288-YC-F(E) | Mouse Anti-TNP Recombinant Antibody (clone IGELb4); Fab Fragment | ELISA | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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