Recombinant Rabbit Antibody (RB86) is capable of binding to Tau.
Figure 1 Monoclonal antibody DC8E8 inhibits pathological tau–tau interaction.
(A) Tau western blots using MAb86 (top) and human tau-specific antibody HT7 (bottom) for detection. MAb86 binds specifically to ERK-phosphorylated tau (lane 1) but not to unphosphorylated tau (lane 2), ERK-phosphorylated mutant tau S422A (lane 3) or unphosphorylated tau S422A (lane 4). (B) Western blots of brain extracts from TauPS2APP mouse brains using MAb86 (top) and human tau-specific antibody HT7 (bottom) for detection. Extracts were prepared from 16-month-old wild-type mice (lane 1) or triple transgenic mice at 8, 12, 16 and 20 months of age (lanes 2-5). M = molecular weight markers.
Collin, L., Bohrmann, B., Göpfert, U., Oroszlan-Szovik, K., Ozmen, L., & Grüninger, F. (2014). Neuronal uptake of tau/pS422 antibody and reduced progression of tau pathology in a mouse model of Alzheimer‘s disease. Brain, 137(10), 2834-2846.
Figure 2 Tau/pS422 locates in lipid raft microdomains on neuronal membranes in untreated TauPS2APP mice.
(A-D) Pathological tau/ pS422 is detected in lipid raft-like microdomains on the periphery of a dendritic shaft (A and B). (C and D) High magnification of the boxed area in B. Microtubule cytoskeleton is in green (B and D), nuclei are counterstained with DAPI in B. (E-G) Tau/pS422 partially localizes with flotillin 1 as indicated by arrows.
Collin, L., Bohrmann, B., Göpfert, U., Oroszlan-Szovik, K., Ozmen, L., & Grüninger, F. (2014). Neuronal uptake of tau/pS422 antibody and reduced progression of tau pathology in a mouse model of Alzheimer‘s disease. Brain, 137(10), 2834-2846.
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• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1215z | Mouse Anti-MAPT Recombinant Antibody (clone 44C4) | ICC, IF, IHC, WB | Mouse IgG1 |
PABL-305 | Chicken Anti-MAPT Recombinant Antibody | WB, ELISA, FuncS | Chicken IgY |
HPAB-0042-WJ | Human Anti-MAPT Recombinant Antibody (HPAB-0042-WJ) | ELISA, WB | Humanized IgG4 |
MRO-1472-CN | Recombinant Rabbit Anti-MAPT Monoclonal Antibody (CBACN-546) | WB, IHC, IP | Rabbit IgG |
MRO-1473-CN | Recombinant Rabbit Anti-MAPT Monoclonal Antibody (CBACN-547) | WB, IF, FC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-340 | Mouse Anti-MAPT Recombinant Antibody (clone AT8); Fab Fragment | ELISA, FuncS | Mouse Fab |
PFBL-674 | Chicken Anti-MAPT Recombinant Antibody (clone pT231/pS235_1); Fab Fragment | WB, ELISA, FACS, Block | Chicken Fab |
HPAB-0042-WJ-F(E) | Human Anti-MAPT Recombinant Antibody; Fab Fragment (HPAB-0042-WJ-F(E)) | ELISA, WB | Humanized Fab |
HPAB-N0170-YC-F(E) | Human Anti-MAPT Recombinant Antibody; Fab Fragment (HPAB-N0170-YC-F(E)) | ELISA, Inhib | Humanized Fab |
HPAB-N0171-YC-F(E) | Human Anti-MAPT Recombinant Antibody; Fab Fragment (HPAB-N0171-YC-F(E)) | ELISA, FuncS | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0733MZ | Chicken Anti-TAU Polyclonal IgY | ICC/IF, IHC, WB | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-174 | Recombinant Mouse Anti-Tau5 Antibody | WB, ELISA, Neut, FuncS | IgG |
PABX-174-S (P) | Recombinant Mouse Anti-Tau5 Antibody scFv Fragment | WB, ELISA, Neut, FuncS | scFv |
PABX-174-F (E) | Recombinant Mouse Anti-Tau5 Antibody Fab Fragment | WB, ELISA, Neut, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-2164 | Hi-Affi™ Recombinant Rabbit Anti-MAPT Monoclonal Antibody (DS2164AB) | IHC-P | IgG |
MOR-4513 | Hi-Affi™ Recombinant Rabbit Anti-MAPT Monoclonal Antibody (TH21DS) | WB, IHC-P, FC | IgG |
MOR-4714 | Hi-Affi™ Recombinant Rabbit Anti-MAPT Monoclonal Antibody (TH228DS) | WB, IF, ICC, IHC-P, FC | IgG |
MOR-4715 | Hi-Affi™ Recombinant Rabbit Anti-MAPT Monoclonal Antibody (TH229DS) | WB, IF, ICC, IHC-P | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
NS-090CN | Mouse Anti-MAPT Recombinant Antibody (NS-090CN) | WB, ELISA, IHC, IP, SPR, FuncS | Mouse IgG2b |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0568-WJ-S(P) | Mouse Anti-MAPT Recombinant Antibody; scFv Fragment (HPAB-0568-WJ-S(P)) | ELISA | Mouse scFv |
HPAB-0569-WJ-S(P) | Mouse Anti-MAPT Recombinant Antibody; scFv Fragment (HPAB-0569-WJ-S(P)) | ELISA | Mouse scFv |
HPAB-0570-WJ-S(P) | Mouse Anti-MAPT Recombinant Antibody; scFv Fragment (HPAB-0570-WJ-S(P)) | ELISA | Mouse scFv |
HPAB-0571-WJ-S(P) | Mouse Anti-MAPT Recombinant Antibody; scFv Fragment (HPAB-0571-WJ-S(P)) | ELISA | Mouse scFv |
HPAB-0572-WJ-S(P) | Mouse Anti-MAPT Recombinant Antibody; scFv Fragment (HPAB-0572-WJ-S(P)) | ELISA | Mouse scFv |
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