Anti-Human VEGF Recombinant Antibody (hEBV321) (CAT#: TAB-302CQ)
The neutralizing antibody is highly specific to human VEGF-A with high affinity (KD=11.5 pM) and does not bind to human VEGF-B, -C, and -D. It blocks VEGF/VEGFR-2 interaction and VEGF-induced receptor phosphorylation.
Specific Inquiry
ELISA
Figure 1 VEGF competition ELISA measuring the binding of hEBV321 to VEGF coated on ELISA plate in the presence of increasing concentration of competitor (hEBV321, Bevacizumab or an irrelevant antibody Humira).
Yu, Y., Lee, P., Ke, Y., Zhang, Y., Yu, Q., Lee, J., ... & Do Couto, F. J. R. (2010). A humanized anti-VEGF rabbit monoclonal antibody inhibits angiogenesis and blocks tumor growth in xenograft models. PloS one, 5(2), e9072.
IHC
Figure 2 Photomicrographs of immunohistochemistry staining with an anti-CD34 mAb (x400). Representative areas of tumor sections from cohorts receiving saline as hEBV321.
Yu, Y., Lee, P., Ke, Y., Zhang, Y., Yu, Q., Lee, J., ... & Do Couto, F. J. R. (2010). A humanized anti-VEGF rabbit monoclonal antibody inhibits angiogenesis and blocks tumor growth in xenograft models. PloS one, 5(2), e9072.
Specifications
- Host Species
- Human
- Type
- Humanized antibody
- Specificity
- Human
- Species Reactivity
- Human, Mouse
- Clone
- hEBV321
- Applications
- ELISA, IHC
- Related Disease
- Lung carcinoma
Applications
- Application Notes
- This antibody has been tested for use in ELISA, Immunohistochemistry. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
Related Resources
Bladder Cancer
Rheumatoid Arthritis
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1036-S(P) | Recombinant Anti-VEGF Antibody scFv Fragment | ELISA, WB, IP, FuncS | scFv |
| HPAB-2819LY-S(P) | Human Anti-VEGF Recombinant Antibody; scFv Fragment (HPAB-2819LY-S(P)) | ELISA, WB | Humanized scfv |
| HPAB-2820LY-S(P) | Human Anti-VEGF Recombinant Antibody; scFv Fragment (HPAB-2820LY-S(P)) | ELISA, WB | Humanized scfv |
| HPAB-J0264-YC-S(P) | Human Anti-VEGF Recombinant Antibody (clone G12); scFv Fragment | ELISA, Neut | Human scFv |
| HPAB-J0265-YC-S(P) | Human Anti-VEGF Recombinant Antibody (clone E9); scFv Fragment | ELISA, Neut | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-1036-F(E) | Recombinant Human Anti-VEGF Antibody Fab Fragment | ELISA, IF, FuncS | Fab |
| PFBZ-130 | Mouse Anti-VEGF Recombinant Antibody (clone 12); Fab Fragment | ELISA, Neut | Mouse Fab |
| PFBW-130 | Mouse Anti-VEGF Recombinant Antibody (clone A4.6.1); Fab Fragment | Neut, ELISA | Mouse Fab |
| PFBC-131 | Human Anti-VEGF Recombinant Antibody (clone B20-4); Fab Fragment | ELISA, Neut, Block | Human Fab |
| HPAB-0746LY-F(E) | Human Anti-VEGF Recombinant Antibody; Fab Fragment (HPAB-0746LY-F(E)) | ELISA | Humanized Fab |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-658CL | Human Anti-VEGF Recombinant Antibody (TAB-658CL) | ELISA | Human IgG |
| TAB-293CQ-F(E) | Anti-Human VEGF Recombinant Antibody Fab Fragment (HAB1) | ELISA, Inhib | Humanized antibody |
| TAB-294CQ-F(E) | Anti-Human VEGF Recombinant Antibody Fab Fragment (hAB2) | ELISA, Inhib | Humanized antibody |
| TAB-407CQ-F(E) | Human Anti-VEGF Recombinant Antibody; Fab Fragment (TAB-407CQ-F(E)) | ELISA | Humanized Fab |
| TAB-408CQ-F(E) | Human Anti-VEGF Recombinant Antibody; Fab Fragment (TAB-408CQ-F(E)) | ELISA | Humanized Fab |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-288CQ | Human Anti-VEGF Recombinant Antibody (TAB-288CQ) | ELISA | Chimeric (Mouse/Human) IgG1, κ |
| TAB-301CQ | Human Anti-VEGF Recombinant Antibody (TAB-301CQ) | ELISA, FC, IHC, WB | Chimeric (Mouse/Human) IgG1, κ |
| TAB-301CQ-F(E) | Human Anti-VEGF Recombinant Antibody; Fab Fragment (TAB-301CQ-F(E)) | ELISA, FC, IHC, WB | Chimeric (Mouse/Human) Fab |
| PABX-185 | Recombinant Human Anti-VEGF Antibody (Fab-12) | ELISA, FuncS | IgG |
| PABX-185-F (E) | Recombinant Mouse Anti-VEGF Antibody Fab Fragment (Fab-12) | ELISA, FuncS | Fab |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-296CQ | Anti-Human VEGF Recombinant Antibody (XPA.10.064) | Inhib | Human antibody |
| TAB-409CQ-S(P) | Human Anti-VEGF Recombinant Antibody; scFv Fragment (TAB-409CQ-S(P)) | ELISA | Human scFv |
| TAB-410CQ-S(P) | Human Anti-VEGF Recombinant Antibody; scFv Fragment (TAB-410CQ-S(P)) | ELISA | Human scFv |
| PABX-186 | Human Anti-VEGF Recombinant Antibody (PABX-186) | WB, ELISA, FuncS | Human IgG |
| PABX-186-F (E) | Human Anti-VEGF Recombinant Antibody; Fab Fragment (PABX-186-F (E)) | WB, ELISA, FuncS | Human Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-285CQ-S(P) | Mouse Anti-VEGF Recombinant Antibody; scFv Fragment (TAB-285CQ-S(P)) | ELISA, WB, Neut | Mouse scFv |
| TAB-287CQ-S(P) | Mouse Anti-VEGF Recombinant Antibody; scFv Fragment (TAB-287CQ-S(P)) | ELISA, WB, IHC, Block | Mouse scFv |
| TAB-290CQ-S(P) | Anti-Human VEGF Recombinant Antibody scFv Fragment | ELISA, WB, Neut | |
| PABX-185-S (P) | Recombinant Mouse Anti-VEGF Antibody scFv Fragment (Fab-12) | ELISA, FuncS | scFv |
| PABX-186-S (P) | Human Anti-VEGF Recombinant Antibody; scFv Fragment (PABX-186-S (P)) | WB, ELISA, FuncS | Human scFv |
Fc Glycosylation
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-096LC | Recombinant Anti-Human VEGF Antibody (Fc glycosylation) | ELISA | Humanized antibody |
| Gly-143LC | Recombinant Anti-Human VEGF Antibody (Fc glycosylation) | ELISA | Humanized antibody |
Deglycosylated Antibody (Non-glycosylated IgGs)
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-179LC | Recombinant Anti-Human VEGF Antibody (Non-glycosylated) | ELISA | Human antibody |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4485 | Rabbit Anti-VEGF Recombinant Antibody (clone SI581DS) | ELISA | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0307LY | Human Anti-VEGF Recombinant Antibody (clone XPA.10.072) | ELISA, Inhib | Human IgG2 |
| HPAB-0746LY | Human Anti-VEGF Recombinant Antibody (HPAB-0746LY) | ELISA | Humanized IgG1 |
| HPAB-1377LY | Mouse Anti-VEGF Recombinant Antibody (HPAB-1377LY) | ELISA, Inhib | Mouse IgG |
| HPAB-2709LY | Human Anti-VEGF Recombinant Antibody (clone YS03) | ELISA | Human IgG |
| HPAB-AP213-YC | Human Anti-VEGF Recombinant Antibody (HPAB-AP213-YC) | ELISA | Human IgG |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-J0267-YC | Recombinant Camelid Anti-VEGF Single Domain Antibody (V9) | ELISA, Neut | Camelid VHH |
| HPAB-J0268-YC | Recombinant Camelid Anti-VEGF Single Domain Antibody (V93) | ELISA, Neut | Camelid VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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