This immunotoxin was achieved by conjugating/fusing the Anti-WT1 monoclonal antibody to ricin toxin. It was expressed in CHO and purified with affinity chromatography. The immunotoxin selectively binds to tumor cells. Then the ricin A chain is incorporated into the cell by receptor-mediated endocytosis, blocking ribosomal protein synthesis and ultimately leading to cell death. It was designed for treatment of T cell leukemia.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1458z | Mouse Anti-WT1 Recombinant Antibody (clone 24C8) | FC, IF, IHC | Mouse IgG1, κ |
MOB-117CQ | Human Anti-WT1 Recombinant Antibody (MOB-117CQ) | ELISA, WB, FC, FuncS | Human IgG1 |
MRO-1597-CN | Rabbit Anti-WT1 Recombinant Antibody (clone CBACN-584) | WB, IF, IHC, FC | Rabbit IgG |
ZG-0040U | Rabbit Anti-WT1 Recombinant Antibody (clone 5F2) | ELISA, WB, IHC | Rabbit IgG |
VS3-XY1601 | Mouse Anti-WT1 Recombinant Antibody (clone 7B11D6) | ELISA, WB, FC | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-3886 | Rabbit Anti-WT1 Recombinant Antibody (clone DS3886AB) | WB, IP | Rabbit IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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