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mitumomab (TAB-764)

Recombinant mouse monoclonal antibody expressed in CHO binding to human ganglioside GD3. Mitumomab is a mouse monoclonal antibody investigated for the treatment of small cell lung carcinoma in combination with BCG vaccination. Mitumomab attacks tumour cells, while the vaccine is thought to activate the immune system.      

Specifications
Immunogen
The details of the immunogen for this antibody are not available.
Host
Mouse
Derivation
Mouse
Type
IgG2b - kappa
Species Reactivity
Human
Applications
Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, ICC and most other immunological methods.
CAS NO.
216503-58-1
Generic Name
mitumomab
Related Disease
Melanoma
Target
Alternative Names
mitumomab;216503-58-1;BEC-2;ST8SIA1;ST8 alpha-N-acetyl-neuraminide alpha-2, 8-sialyltransferase 1;sialyltransferase 8 (alpha N acetylneuraminate: alpha 2, 8 sialytransferase, GD3 synthase) A , SIAT8, SIAT8A;alpha-N-acetylneuraminide alpha-2, 8-sialyltrans
Entrez Gene ID
6489
UniProt ID
Q92185

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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