BV421-DRB*01:01/Human COL2A1 (AGFKGEQGPKGEPG) MHC Tetramer (CAT#: MHC-LC1336)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of COL2A1-derived peptide of AGFKGEQGPKGEPG covering 461-474 and DRB*01:01 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.


Specific Inquiry
  • Size:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Allele
  • DRB*01:01
  • Class
  • Class II
  • Antigen
  • COL2A1
  • Antigen Species
  • Human
  • Peptide
  • AGFKGEQGPKGEPG
  • Range
  • 461-474
  • Conjugate
  • BV421
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia.
  • Alternative Names
  • COL2A1; collagen type II alpha 1 chain; AOM; ANFH; SEDC; STL1; COL11A3

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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