Products

Anti-CD19 × Anti-CD22 Bispecific Antibody (BiTE, DT2219ARL) (BSAB-L014)

Recombinant Anti-CD19 × Anti-CD22 Bi-specific T-cell engagers (BiTE) expressed as a single-chain Fv (scFv) from anti-CD19 VH and VL region fused with a scFv of anti-CD22 VH and VL region with a His-tag at the C-terminus. This BsAb exists as a monomer under non-reducing and reducing condition. It was designed for the treatment of B cell leukmia or lymphoma.      

Specifications
Targets
CD19 & CD22
Type
BiTE
Expression Host
CHO
Species Reactivity
Human
Target 1
CD19
Host
Mouse IgG1 κ
Clone
HD37
Target 2
CD22
Host
Mouse IgG1
Clone
RFB4
Purity
>95% judged by SDS-PAGE under reducing condition
Related Disease
B cell leukmia or lymphoma
Targets
Target 1
CD19
Gene ID
930
UniProt ID
P15391
Alternative Names
B4; CVID3
Target 2
CD22
Gene ID
933
UniProt ID
P20273
Alternative Names
SIGLEC2; SIGLEC-2

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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