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Anti-CD19 × Anti-CD3 Bispecific Antibody (TandAb, AFM11) (BSAB-L011)

Recombinant Anti-CD19 × Anti-CD3 Bispecific Antibody (TandAb). This bsAb has been generated by applying the Crossmab format to generate an IgGshaped entity that binds each ligand with one arm. The complex is capable of Retargeting of T cells to tumor. It was designed for the treatment of NHL and ALL.      

Specifications
Targets
CD19 & CD3
Type
TandAb
Expression Host
CHO
Species Reactivity
Human
Target 1
CD19
Host
Humanized
Clone
huHD37
Target 2
CD3
Host
Mouse
Clone
OKT3
Purity
>95% judged by SDS-PAGE under reducing condition
Related Disease
ALL (acute lymphoblastic leukemia), NHL (non-hodgkin lymphoma)
Targets
Target 1
CD19
Gene ID
930
UniProt ID
P15391
Alternative Names
B4; CVID3
Target 2
CD3
Alternative Names
CD3; cluster of differentiation 3; CD3γ; CD3δ; CD3ε; CD3ζ

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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