Products

Anti-CEA × Anti-GD2 Bispecific Antibody (DVD-L015)

Recombinant Anti-CEA & Anti-GD2 Bispecific Antibody (DVD-Ig) was used comprised a whole CEA-binding 'IgG' (with Fc region) to which additional variable regions that bind GD2 were fused 'on top' of the existing variable regions. It was designed for the treatment of neuroblastoma and osteosarcoma.      

Specifications
Targets
CEA & GD2
Type
DVD-Ig
Expression Host
CHO
Species Reactivity
Human
Target 1
CEA
Host
Human
Clone
35A7
Target 2
GD2
Host
Human
Purity
>95% judged by SDS-PAGE under reducing condition
Applications
FuncS, Promising therapeutic agent
Related Disease
Neuroblastoma and Osteosarcoma
Targets
Target 1
CEA
Gene ID
1048
UniProt ID
A0A024R0K5
Alternative Names
CEACAM5; carcinoembryonic antigen-related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100
Target 2
GD2
Alternative Names
Ganglioside G2; GD2; Ganglioside

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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