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Anti-CSPG4 × Anti-CD3 Bi-specific T-cell engagers (BiTE, MCSP-G4 HL x H2C HL) (BITE-LC019)

The anti-CD3/MCSP antibody specifically binds to CD3 and MCSP. By inducing T Cell mediated target cell lysis, the antibody can be potentially used in the treatment of cancers such as malignant melanoma.      

Specifications
Targets
MCSP & CD3
Type
BiTE
Expression Host
CHO
Species Reactivity
Human
Target 1
MCSP
Host
Human
Clone
H2C
Target 2
CD3
Host
Human
Clone
G4H
Purity
>95% judged by SDS-PAGE under reducing condition
Applications
FC
Related Disease
Malignant melanoma
Targets
Target 1
MCSP
Gene ID
1464
UniProt ID
Q6UVK1
Alternative Names
CSPG4; chondroitin sulfate proteoglycan 4; NG2; MCSP; MCSPG; MSK16; HMW-MAA; MEL-CSPG
Target 2
CD3
Alternative Names
CD3; CD3 T-Cell Co-receptor;CD3D; CD3E; CD3G

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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